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Statements

Subject Item
n2:RIV%2F61989592%3A15260%2F14%3A33151582%21RIV15-MSM-15260___
rdf:type
n12:Vysledek skos:Concept
dcterms:description
Purpose: Bladder, bowel and sexual dysfunction are often overlooked symptoms in patients with multiple sclerosis (MS) and can be associated with lower health-related quality of life (HRQoL). The aim is to explore the association of bladder, bowel and sexual dysfunction with HRQoL in MS patients stratified by disease duration ({= 5 and } 5 years) and controlled for clinical and sociodemographic variables. Methods: The study comprised 223 MS patients (mean age 38.9 +/- 10.8 years, 67% female, mean EDSS 3.0 +/- 1.5) who filled out the Short-Form-36 Health Survey, the Bladder Control Scale, the Bowel Control Scale and the Incapacity Status Scale. The relationships between the variables were analyzed with multiple linear regression using the SF36's Physical Component Summary (PCS) and Mental Component Summary (MCS) as dependent variables. Results: More severe bladder dysfunction was associated with lower PCS in both disease duration groups (beta= -0.35, p {= 0.001 versus beta = -0.43, p {= 0.001), whereas more severe sexual dysfunction was associated with lower MCS in the group with shorter disease duration (beta= -0.23, p {= 0.05). Conclusion: Bladder and sexual dysfunction are associated with a poorer HRQoL in MS patients even if they have had MS for a relatively short time. Recognition and proper treatment is needed to prevent the development of more severe dysfunction; this may also lead to a better HRQoL. Purpose: Bladder, bowel and sexual dysfunction are often overlooked symptoms in patients with multiple sclerosis (MS) and can be associated with lower health-related quality of life (HRQoL). The aim is to explore the association of bladder, bowel and sexual dysfunction with HRQoL in MS patients stratified by disease duration ({= 5 and } 5 years) and controlled for clinical and sociodemographic variables. Methods: The study comprised 223 MS patients (mean age 38.9 +/- 10.8 years, 67% female, mean EDSS 3.0 +/- 1.5) who filled out the Short-Form-36 Health Survey, the Bladder Control Scale, the Bowel Control Scale and the Incapacity Status Scale. The relationships between the variables were analyzed with multiple linear regression using the SF36's Physical Component Summary (PCS) and Mental Component Summary (MCS) as dependent variables. Results: More severe bladder dysfunction was associated with lower PCS in both disease duration groups (beta= -0.35, p {= 0.001 versus beta = -0.43, p {= 0.001), whereas more severe sexual dysfunction was associated with lower MCS in the group with shorter disease duration (beta= -0.23, p {= 0.05). Conclusion: Bladder and sexual dysfunction are associated with a poorer HRQoL in MS patients even if they have had MS for a relatively short time. Recognition and proper treatment is needed to prevent the development of more severe dysfunction; this may also lead to a better HRQoL.
dcterms:title
Health-related quality of life in multiple sclerosis patients with bladder, bowel and sexual dysfunction Health-related quality of life in multiple sclerosis patients with bladder, bowel and sexual dysfunction
skos:prefLabel
Health-related quality of life in multiple sclerosis patients with bladder, bowel and sexual dysfunction Health-related quality of life in multiple sclerosis patients with bladder, bowel and sexual dysfunction
skos:notation
RIV/61989592:15260/14:33151582!RIV15-MSM-15260___
n3:aktivita
n17:P
n3:aktivity
P(EE.2.3.20.0063)
n3:cisloPeriodika
12
n3:dodaniDat
n14:2015
n3:domaciTvurceVysledku
Dijk, Jitse P. Van
n3:druhVysledku
n6:J
n3:duvernostUdaju
n15:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
18848
n3:idVysledku
RIV/61989592:15260/14:33151582
n3:jazykVysledku
n8:eng
n3:klicovaSlova
sexual dysfunction; quality of life; multiple sclerosis; bowel dysfunction; Bladder dysfunction
n3:klicoveSlovo
n5:sexual%20dysfunction n5:multiple%20sclerosis n5:Bladder%20dysfunction n5:quality%20of%20life n5:bowel%20dysfunction
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[8FF9E900CFF7]
n3:nazevZdroje
Disability and Rehabilitation
n3:obor
n11:FQ
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
7
n3:projekt
n13:EE.2.3.20.0063
n3:rokUplatneniVysledku
n14:2014
n3:svazekPeriodika
36
n3:tvurceVysledku
Vítková, Marriana Gdovinová, Zuzana Rosenberger, Jaroslav Dijk, Jitse P. Van Szilasiová, Jarmila Groothoff, Johan W Krokavcová, Martina
s:issn
0963-8288
s:numberOfPages
6
n9:organizacniJednotka
15260