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Statements

Subject Item
n2:RIV%2F61989592%3A15260%2F14%3A33151524%21RIV15-MSM-15260___
rdf:type
skos:Concept n17:Vysledek
dcterms:description
Aim: This study explores the association between kidney function, side effects of immunosuppressive treatment, coping self-efficacy, and physical and mental HRQoL at 3 months (baseline) after kidney transplantation (KT) and their impact on patient and graft survival for up to 10 years (follow-up). Methods: A group of 151 patients provided at baseline their socioeconomic and medical (CKD-EPI) data and completed the End-Stage Renal Disease Symptom Checklist (perceived side effects), the coping self-efficacy scale, and the SF-36. At follow-up, patients' health status was noted. Univariate GLM exploring the main effects of the independent variables on physical and mental HRQoL was performed; furthermore, Cox regression analyses were performed to determine whether the early posttransplantation factors predicted patient and graft survival. Results: Less severe side effects of immunosuppressive treatment and higher efficacy in stopping unpleasant emotions were associated with both higher physical and mental HRQoL at baseline. Younger age was associated with higher physical HRQoL and older age, and lower efficacy in getting support from family and friend were associated with higher mental HRQoL. Patients reporting higher physical and mental HRQoL at 3 months and with higher age and better kidney function had higher odds of surviving with a functioning graft. Conclusion: Older age, higher kidney function, and higher physical and mental HRQoL at baseline significantly improved the odds of graft and patient survival over 10 years. These results show the importance of close monitoring of early posttransplantation HRQoL along with kidney function and reported side effects because of their effect on long-term patient outcomes. Aim: This study explores the association between kidney function, side effects of immunosuppressive treatment, coping self-efficacy, and physical and mental HRQoL at 3 months (baseline) after kidney transplantation (KT) and their impact on patient and graft survival for up to 10 years (follow-up). Methods: A group of 151 patients provided at baseline their socioeconomic and medical (CKD-EPI) data and completed the End-Stage Renal Disease Symptom Checklist (perceived side effects), the coping self-efficacy scale, and the SF-36. At follow-up, patients' health status was noted. Univariate GLM exploring the main effects of the independent variables on physical and mental HRQoL was performed; furthermore, Cox regression analyses were performed to determine whether the early posttransplantation factors predicted patient and graft survival. Results: Less severe side effects of immunosuppressive treatment and higher efficacy in stopping unpleasant emotions were associated with both higher physical and mental HRQoL at baseline. Younger age was associated with higher physical HRQoL and older age, and lower efficacy in getting support from family and friend were associated with higher mental HRQoL. Patients reporting higher physical and mental HRQoL at 3 months and with higher age and better kidney function had higher odds of surviving with a functioning graft. Conclusion: Older age, higher kidney function, and higher physical and mental HRQoL at baseline significantly improved the odds of graft and patient survival over 10 years. These results show the importance of close monitoring of early posttransplantation HRQoL along with kidney function and reported side effects because of their effect on long-term patient outcomes.
dcterms:title
Health-Related Quality of Life 3 months after kidney transplantation as a predictor of survival over 10 years: a longitudinal study. Health-Related Quality of Life 3 months after kidney transplantation as a predictor of survival over 10 years: a longitudinal study.
skos:prefLabel
Health-Related Quality of Life 3 months after kidney transplantation as a predictor of survival over 10 years: a longitudinal study. Health-Related Quality of Life 3 months after kidney transplantation as a predictor of survival over 10 years: a longitudinal study.
skos:notation
RIV/61989592:15260/14:33151524!RIV15-MSM-15260___
n3:aktivita
n14:P
n3:aktivity
P(EE.2.3.20.0063)
n3:cisloPeriodika
11
n3:dodaniDat
n10:2015
n3:domaciTvurceVysledku
Dijk, Jitse P. Van
n3:druhVysledku
n15:J
n3:duvernostUdaju
n4:S
n3:entitaPredkladatele
n9:predkladatel
n3:idSjednocenehoVysledku
18849
n3:idVysledku
RIV/61989592:15260/14:33151524
n3:jazykVysledku
n11:eng
n3:klicovaSlova
Side effects; Survival; Transplantation; Kidney; Health-related quality of life; Coping
n3:klicoveSlovo
n7:Survival n7:Kidney n7:Side%20effects n7:Transplantation n7:Coping n7:Health-related%20quality%20of%20life
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[B77ACC60DED3]
n3:nazevZdroje
Transplantation
n3:obor
n8:FQ
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
7
n3:projekt
n16:EE.2.3.20.0063
n3:rokUplatneniVysledku
n10:2014
n3:svazekPeriodika
97
n3:tvurceVysledku
Rosenberger, Jaroslav Nagyová, Iveta Majerníková, Mária Roland, Robert Príhodová, Lucia Groothoff, Johan W Dijk, Jitse P. Van
s:issn
0041-1337
s:numberOfPages
7
n13:organizacniJednotka
15260