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Statements

Subject Item
n2:RIV%2F61989592%3A15110%2F14%3A33151032%21RIV15-MSM-15110___
rdf:type
skos:Concept n17:Vysledek
dcterms:description
BACKGROUND: Photodynamic therapy (PDT) is linked with oxidative damage of biomolecules causing significant impairment of essential cellular functions that lead to cell death. It is the reason why photodynamic therapy has found application in treatment of different oncological, cardiovascular, skin and eye diseases. Efficacy of PDT depends on combined action of three components; sensitizer, light and oxygen. In the present study, we examined whether higher partial pressure of oxygen increases lethality in HeLa cell lines exposed to light in the presence of chloraluminium phthalocyanine disulfonate (ClAlPcS2). BACKGROUND: Photodynamic therapy (PDT) is linked with oxidative damage of biomolecules causing significant impairment of essential cellular functions that lead to cell death. It is the reason why photodynamic therapy has found application in treatment of different oncological, cardiovascular, skin and eye diseases. Efficacy of PDT depends on combined action of three components; sensitizer, light and oxygen. In the present study, we examined whether higher partial pressure of oxygen increases lethality in HeLa cell lines exposed to light in the presence of chloraluminium phthalocyanine disulfonate (ClAlPcS2).
dcterms:title
High Oxygen Partial Pressure Increases Photodynamic Effect on HeLa Cell Lines in the Presence of Chloraluminium Phtalocyanine High Oxygen Partial Pressure Increases Photodynamic Effect on HeLa Cell Lines in the Presence of Chloraluminium Phtalocyanine
skos:prefLabel
High Oxygen Partial Pressure Increases Photodynamic Effect on HeLa Cell Lines in the Presence of Chloraluminium Phtalocyanine High Oxygen Partial Pressure Increases Photodynamic Effect on HeLa Cell Lines in the Presence of Chloraluminium Phtalocyanine
skos:notation
RIV/61989592:15110/14:33151032!RIV15-MSM-15110___
n3:aktivita
n16:P
n3:aktivity
P(EE2.3.30.0004)
n3:cisloPeriodika
8
n3:dodaniDat
n5:2015
n3:domaciTvurceVysledku
n4:3611949 n4:2758253 n4:8827354 n4:6614132 n4:4906403 n4:6804454
n3:druhVysledku
n18:J
n3:duvernostUdaju
n6:S
n3:entitaPredkladatele
n7:predkladatel
n3:idSjednocenehoVysledku
19071
n3:idVysledku
RIV/61989592:15110/14:33151032
n3:jazykVysledku
n15:eng
n3:klicovaSlova
hyperoxia.; reactive oxygen species; Photodynamic therapy
n3:klicoveSlovo
n11:hyperoxia. n11:reactive%20oxygen%20species n11:Photodynamic%20therapy
n3:kodStatuVydavatele
GR - Řecká republika
n3:kontrolniKodProRIV
[00C476193F43]
n3:nazevZdroje
Anticancer Research
n3:obor
n13:BO
n3:pocetDomacichTvurcuVysledku
6
n3:pocetTvurcuVysledku
6
n3:projekt
n9:EE2.3.30.0004
n3:rokUplatneniVysledku
n5:2014
n3:svazekPeriodika
34
n3:tvurceVysledku
Bajgar, Robert Pížová, Klára Hanáková, Adéla Bolek, Lukáš Binder, Svatopluk Kolářová, Hana
n3:wos
000339773400028
s:issn
0250-7005
s:numberOfPages
5
n10:organizacniJednotka
15110