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Subject Item
n2:RIV%2F61989592%3A15110%2F13%3A33147552%21RIV14-MSM-15110___
rdf:type
skos:Concept n10:Vysledek
dcterms:description
Abstract AIM: To find out whether it is possible to anaesthetize patients safely without analgesia and sedation, using burst pacing prolonged until the patient becomes unconscious. METHODS: One hundred and four patients undergoing implantation or reimplantation of a cardioverter-defibrillator were included. Patients randomized into Group B underwent prolonged burst pacing without analgesia and sedation. Patients in Group T underwent a T-wave shock under analgesia and sedation. Blood samples for measurement of serum neuron-specific enolase were taken before surgery and 6, 24, and 48 h after the procedure. RESULTS: From the 104 patients, 51 were randomly assigned to Group B and 53 to Group T. Four patients from Group B were switched to Group T (ventricular fibrillation not induced by burst pacing). The clinical characteristics of both groups were similar. The mean total time of cardiac arrest was significantly longer in Group B (23.0 +- 4.4 s, median 22.7) vs. Group T (10.3 +- 3.0 s, median 10.0), P { 0.0001 (Mann-Whitney U-test). The effectiveness of both induction methods was similar (92.1% in Group B and 100% in Group T). The mean neuron-specific enolase levels after 6, 24, and 48 h were similar in Groups B and T (13.1 +- 6.3 and 11.6 +- 5.8 mg/L, 14.5 +- 7.5 and 13.4 +- 6.0 mg/L, and 14.9 +- 5.9 and 12.2 +- 6.0 mg/L, respectively) as were these levels compared with baseline neuron-specificenolase levels (14.0 +- 5.9 and 13.4 +- 4.0 mg/L, respectively), P = NS for all. CONCLUSION: Despite a longer time of total cardiac arrest, prolonged burst pacing appears to be a safe and effective method for induction of ventricular fibrillation during cardioverter-defibrillator testing, which enables omission of analgesia and sedation or general anaesthesia. PMID: 23089188 [PubMed - indexed for MEDLINE] Free full text Abstract AIM: To find out whether it is possible to anaesthetize patients safely without analgesia and sedation, using burst pacing prolonged until the patient becomes unconscious. METHODS: One hundred and four patients undergoing implantation or reimplantation of a cardioverter-defibrillator were included. Patients randomized into Group B underwent prolonged burst pacing without analgesia and sedation. Patients in Group T underwent a T-wave shock under analgesia and sedation. Blood samples for measurement of serum neuron-specific enolase were taken before surgery and 6, 24, and 48 h after the procedure. RESULTS: From the 104 patients, 51 were randomly assigned to Group B and 53 to Group T. Four patients from Group B were switched to Group T (ventricular fibrillation not induced by burst pacing). The clinical characteristics of both groups were similar. The mean total time of cardiac arrest was significantly longer in Group B (23.0 +- 4.4 s, median 22.7) vs. Group T (10.3 +- 3.0 s, median 10.0), P { 0.0001 (Mann-Whitney U-test). The effectiveness of both induction methods was similar (92.1% in Group B and 100% in Group T). The mean neuron-specific enolase levels after 6, 24, and 48 h were similar in Groups B and T (13.1 +- 6.3 and 11.6 +- 5.8 mg/L, 14.5 +- 7.5 and 13.4 +- 6.0 mg/L, and 14.9 +- 5.9 and 12.2 +- 6.0 mg/L, respectively) as were these levels compared with baseline neuron-specificenolase levels (14.0 +- 5.9 and 13.4 +- 4.0 mg/L, respectively), P = NS for all. CONCLUSION: Despite a longer time of total cardiac arrest, prolonged burst pacing appears to be a safe and effective method for induction of ventricular fibrillation during cardioverter-defibrillator testing, which enables omission of analgesia and sedation or general anaesthesia. PMID: 23089188 [PubMed - indexed for MEDLINE] Free full text
dcterms:title
Prolonged burst as a new method for cardioverter-defibrillator testing Prolonged burst as a new method for cardioverter-defibrillator testing
skos:prefLabel
Prolonged burst as a new method for cardioverter-defibrillator testing Prolonged burst as a new method for cardioverter-defibrillator testing
skos:notation
RIV/61989592:15110/13:33147552!RIV14-MSM-15110___
n10:predkladatel
n11:orjk%3A15110
n3:aktivita
n15:I
n3:aktivity
I
n3:cisloPeriodika
1
n3:dodaniDat
n6:2014
n3:domaciTvurceVysledku
n5:8525455 n5:4423909 n5:1622536 n5:4472055 n5:2348411
n3:druhVysledku
n16:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n14:predkladatel
n3:idSjednocenehoVysledku
100283
n3:idVysledku
RIV/61989592:15110/13:33147552
n3:jazykVysledku
n9:eng
n3:klicovaSlova
testing; cardioverter-defibrillator; method; new; burst; Prolonged
n3:klicoveSlovo
n4:method n4:Prolonged n4:cardioverter-defibrillator n4:testing n4:new n4:burst
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[565FF40ABE55]
n3:nazevZdroje
Europace
n3:obor
n7:FA
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
7
n3:rokUplatneniVysledku
n6:2013
n3:svazekPeriodika
15
n3:tvurceVysledku
Táborský, Miloš Lukl, Jan Schneiderka, Petr Fedorco, Marián Bulava, Alan Marek, Dan Zapletalová, Jana
n3:wos
000312642400014
s:issn
1099-5129
s:numberOfPages
5
n12:doi
10.1093/europace/eus250
n19:organizacniJednotka
15110