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Statements

Subject Item
n2:RIV%2F61989592%3A15110%2F13%3A33143933%21RIV14-TA0-15110___
rdf:type
n3:Vysledek skos:Concept
dcterms:description
The invention relates to a method for determining the sensitivity of patients suftering from a cancer disease towards targeted biological therapy based on the inhibition of signaling pathways of the members of HER family (e.g., HER-I, HER -2, HER -3 and HER -4) by determining the expression of the biomarker S6 kinase or its post-translationally modified form or of the biomarkers of the aetivation of S6 kinase or their post-translationally modified forms in the tumor. The invention relates to a method for determining the sensitivity of patients suftering from a cancer disease towards targeted biological therapy based on the inhibition of signaling pathways of the members of HER family (e.g., HER-I, HER -2, HER -3 and HER -4) by determining the expression of the biomarker S6 kinase or its post-translationally modified form or of the biomarkers of the aetivation of S6 kinase or their post-translationally modified forms in the tumor.
dcterms:title
METHOD FOR DETERMINING THE SENSITIVITY OF PATIENTS SUFFERING FROM A CANCER DISEASE TO BIOLOGICAL THERAPY METHOD FOR DETERMINING THE SENSITIVITY OF PATIENTS SUFFERING FROM A CANCER DISEASE TO BIOLOGICAL THERAPY
skos:prefLabel
METHOD FOR DETERMINING THE SENSITIVITY OF PATIENTS SUFFERING FROM A CANCER DISEASE TO BIOLOGICAL THERAPY METHOD FOR DETERMINING THE SENSITIVITY OF PATIENTS SUFFERING FROM A CANCER DISEASE TO BIOLOGICAL THERAPY
skos:notation
RIV/61989592:15110/13:33143933!RIV14-TA0-15110___
n3:predkladatel
n17:orjk%3A15110
n4:aktivita
n13:P
n4:aktivity
P(ED0030/01/01), P(TE01020028)
n4:cisloPatentuVzoru
JP5295268
n4:datumUdeleniPatentuVzoru
2013-06-21+02:00
n4:dodaniDat
n11:2014
n4:domaciTvurceVysledku
n12:7608543 n12:5281415 n12:1314335
n4:druhVysledku
n21:P
n4:duvernostUdaju
n23:S
n4:entitaPredkladatele
n5:predkladatel
n4:idSjednocenehoVysledku
87545
n4:idVysledku
RIV/61989592:15110/13:33143933
n4:jazykVysledku
n18:jap
n4:klicovaSlova
biological therapy; cancer; sensitivity
n4:klicoveSlovo
n15:cancer n15:sensitivity n15:biological%20therapy
n4:kontrolniKodProRIV
[E30410BBC15E]
n4:licencniPoplatek
n22:A
n4:mistoVydaniPatentuVzoru
Tokyo
n4:nazevVydavatelePatentuVzoru
Japan Patent Office (JPO)
n4:obor
n8:FD
n4:pocetDomacichTvurcuVysledku
3
n4:pocetTvurcuVysledku
4
n4:projekt
n10:TE01020028 n10:ED0030%2F01%2F01
n4:rokUplatneniVysledku
n11:2013
n4:statVydaniPatentuVzoru
n9:JP
n4:tvurceVysledku
Hajdúch, Marián Radová, Lenka Svoboda, Marek Dziechciarková, Marta
n4:uzemniOchranaPatentu
n6:C
n4:vlastnik
n5:vlastnikVysledku
n4:vyuzitiJinymSubjektem
n20:A
n4:vyuzitiPatentuVzoru
n19:A
n4:vlastnikPatentuVzoru
Univerzita Palackého v Olomouci, Lékařská fakulta; Masarykův onkologický ústav, Brno
n16:organizacniJednotka
15110