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Statements

Subject Item
n2:RIV%2F61989592%3A15110%2F11%3A10224237%21RIV12-MSM-15110___
rdf:type
skos:Concept n11:Vysledek
dcterms:description
Schizophrenia is a complex, multifactorial psychiatric disorder. Our previous findings indicated that altered functional activity of the complement system, a major mediator of the immune response, is implicated in the pathogenesis of schizophrenia. In order to explore whether these alterations are genetically determined or not, in the present study we evaluated the possible association of complement C1Q component gene variants with susceptibility to schizophrenia in Armenian population, focusing on four frequent single nucleotide polymorphisms (SNPs) of C1QA and C1QB genes. Schizophrenia is a complex, multifactorial psychiatric disorder. Our previous findings indicated that altered functional activity of the complement system, a major mediator of the immune response, is implicated in the pathogenesis of schizophrenia. In order to explore whether these alterations are genetically determined or not, in the present study we evaluated the possible association of complement C1Q component gene variants with susceptibility to schizophrenia in Armenian population, focusing on four frequent single nucleotide polymorphisms (SNPs) of C1QA and C1QB genes.
dcterms:title
Association of C1QB gene polymorphism with schizophrenia in Armenian population Association of C1QB gene polymorphism with schizophrenia in Armenian population
skos:prefLabel
Association of C1QB gene polymorphism with schizophrenia in Armenian population Association of C1QB gene polymorphism with schizophrenia in Armenian population
skos:notation
RIV/61989592:15110/11:10224237!RIV12-MSM-15110___
n11:predkladatel
n17:orjk%3A15110
n3:aktivita
n16:S n16:Z
n3:aktivity
S, Z(MSM6198959205)
n3:cisloPeriodika
126
n3:dodaniDat
n18:2012
n3:domaciTvurceVysledku
n10:1507109 n10:6090788 n10:2265397
n3:druhVysledku
n15:J
n3:duvernostUdaju
n19:S
n3:entitaPredkladatele
n6:predkladatel
n3:idSjednocenehoVysledku
187328
n3:idVysledku
RIV/61989592:15110/11:10224237
n3:jazykVysledku
n8:eng
n3:klicovaSlova
Armenian population; schizophrenia; C1QB gene polymorphism
n3:klicoveSlovo
n5:C1QB%20gene%20polymorphism n5:schizophrenia n5:Armenian%20population
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[3F8EB35267B8]
n3:nazevZdroje
BMC Medical Genetics
n3:obor
n13:EC
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
8
n3:rokUplatneniVysledku
n18:2011
n3:svazekPeriodika
12
n3:tvurceVysledku
Zakharyan, Roksana Gevorgyan, Anaida Sťahelová, Anna Khoyetsyan, Aren Boyajyan, Anna Petřek, Martin Arakelyan, Arsen Mrázek, František
n3:zamer
n14:MSM6198959205
s:issn
1471-2350
s:numberOfPages
6
n7:organizacniJednotka
15110