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Statements

Subject Item
n2:RIV%2F61989592%3A15110%2F09%3A00009526%21RIV10-MSM-15110___
rdf:type
skos:Concept n12:Vysledek
dcterms:description
We report a case of acute liver injury probably due to fenofibrate. A 50-year-old female without a history of liver disease developed cholestatic hepatitis during her second week of fenofibrate treatment. Laboratory tests on admission showed serum bilirubin 534?0 mcmol/L (conjugated 444?0), alkaline phosphatase (AP) 8?76, gamma-glutamyl traspeptidase (GGT) 20?92, alanine aminotransferase (ALT) 2?6, aspartate aminotransferase (AST) 3?64 mckat/L. Fenofibrate withdrawal and ursodeoxycholic acid (750 mg daily) administration was rapidly followed by a favourable outcome. We report a case of acute liver injury probably due to fenofibrate. A 50-year-old female without a history of liver disease developed cholestatic hepatitis during her second week of fenofibrate treatment. Laboratory tests on admission showed serum bilirubin 534?0 mcmol/L (conjugated 444?0), alkaline phosphatase (AP) 8?76, gamma-glutamyl traspeptidase (GGT) 20?92, alanine aminotransferase (ALT) 2?6, aspartate aminotransferase (AST) 3?64 mckat/L. Fenofibrate withdrawal and ursodeoxycholic acid (750 mg daily) administration was rapidly followed by a favourable outcome.
dcterms:title
Acute cholestatic hepatitis induced by fenofibrate Acute cholestatic hepatitis induced by fenofibrate
skos:prefLabel
Acute cholestatic hepatitis induced by fenofibrate Acute cholestatic hepatitis induced by fenofibrate
skos:notation
RIV/61989592:15110/09:00009526!RIV10-MSM-15110___
n3:aktivita
n7:Z
n3:aktivity
Z(MSM6198959216)
n3:cisloPeriodika
5
n3:dodaniDat
n15:2010
n3:domaciTvurceVysledku
n4:6691404 n4:9012958 n4:5817854 n4:8644500
n3:druhVysledku
n10:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n9:predkladatel
n3:idSjednocenehoVysledku
301878
n3:idVysledku
RIV/61989592:15110/09:00009526
n3:jazykVysledku
n11:eng
n3:klicovaSlova
adverse effects; anticholesteremic agents; cholestatic hepatitis; fenofibrate; liver diseases
n3:klicoveSlovo
n8:anticholesteremic%20agents n8:fenofibrate n8:liver%20diseases n8:cholestatic%20hepatitis n8:adverse%20effects
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[960929AE0CDF]
n3:nazevZdroje
Journal of Clinical Pharmacy and Therapeutics
n3:obor
n13:FR
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
4
n3:rokUplatneniVysledku
n15:2009
n3:svazekPeriodika
34
n3:tvurceVysledku
Hajdu, Dominika Aiglová, Květoslava Vinklerová, Ilona Urbánek, Karel
n3:zamer
n17:MSM6198959216
s:issn
0269-4727
s:numberOfPages
4
n16:organizacniJednotka
15110