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Statements

Subject Item
n2:RIV%2F61989592%3A15110%2F07%3A10223780%21RIV12-MSM-15110___
rdf:type
skos:Concept n8:Vysledek
dcterms:description
Matrix metalloproteinases (MMPs) belong to proteolytic enzymes. Degradation of the cell basement membrane and the extracellular matrix is one of their functions. In malignant tumors they can hypothetically contribute to the invasion and metastasis formation. They are mostly produced by stromal cells (fibroblasts and endothelial cells) as a response to the presence of tumor cells. MMP-2 (gelatinase A), MMP-9 (gelatinase B) and MMP-11 (stromelysin 3) are often mentioned in regard to Non-small Cell Lung Cancer (NSCLC). Methods and Results. Matrix metalloproteinases (MMPs) belong to proteolytic enzymes. Degradation of the cell basement membrane and the extracellular matrix is one of their functions. In malignant tumors they can hypothetically contribute to the invasion and metastasis formation. They are mostly produced by stromal cells (fibroblasts and endothelial cells) as a response to the presence of tumor cells. MMP-2 (gelatinase A), MMP-9 (gelatinase B) and MMP-11 (stromelysin 3) are often mentioned in regard to Non-small Cell Lung Cancer (NSCLC). Methods and Results.
dcterms:title
Prognostic Impact of Matrix Metalloproteinases 2,9, and 11 in Stromal Cells Stage I Non-small Cell Lung Cancer Prognostic Impact of Matrix Metalloproteinases 2,9, and 11 in Stromal Cells Stage I Non-small Cell Lung Cancer
skos:prefLabel
Prognostic Impact of Matrix Metalloproteinases 2,9, and 11 in Stromal Cells Stage I Non-small Cell Lung Cancer Prognostic Impact of Matrix Metalloproteinases 2,9, and 11 in Stromal Cells Stage I Non-small Cell Lung Cancer
skos:notation
RIV/61989592:15110/07:10223780!RIV12-MSM-15110___
n3:aktivita
n10:I
n3:aktivity
I
n3:cisloPeriodika
146
n3:dodaniDat
n15:2012
n3:domaciTvurceVysledku
n7:6521681 n7:7444540 n7:9905472 n7:8692386 n7:8104360
n3:druhVysledku
n12:J
n3:duvernostUdaju
n5:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
445061
n3:idVysledku
RIV/61989592:15110/07:10223780
n3:jazykVysledku
n11:eng
n3:klicovaSlova
matrix metalloproteinases; stromal cells; non-small cell lung cancer
n3:klicoveSlovo
n4:non-small%20cell%20lung%20cancer n4:stromal%20cells n4:matrix%20metalloproteinases
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[49AFDB510FB7]
n3:nazevZdroje
Časopis lékařů českých
n3:obor
n13:FJ
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
5
n3:rokUplatneniVysledku
n15:2007
n3:svazekPeriodika
1
n3:tvurceVysledku
Dráč, Petr Tichý, Tomáš Kolek, Vítězslav Škarda, Jozef Klein, Jiří
s:issn
0008-7335
s:numberOfPages
3
n17:organizacniJednotka
15110