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Statements

Subject Item
n2:RIV%2F61988987%3A17110%2F13%3AA140181Q%21RIV14-MSM-17110___
rdf:type
n11:Vysledek skos:Concept
dcterms:description
The aim of the present study was to determine the effect of ketamine/xylazine and pentobarbital anaesthesia on heart rate variability as a marker of autonomic nervous system activity. The experiments were performed in ketamine/xylazine (10 mg/kg/15 mg/kg) and pentobarbital (40 mg/kg, i.p.) anaesthetized female Wistar rats, after adaptation to a light-dark cycle of 12 hours light: 12 hours dark. Heart rate variability parameters (RR interval, power VLF (very low frequency), power LF (low frequency), power HF (high frequency) and relative powers) were evaluated during spontaneous breathing as a function of the light-dark cycle (LD cycle). Ketamine/xylazine anaesthesia increased parasympathetic activity, and suppressed sympathetic and baroreceptor activity independently of the light-dark cycle. Pentobarbital anaesthesia increased parasympathetic activity, decreased sympathetic and baroreceptor activity, and eliminated LD differences in RR interval duration. The aim of the present study was to determine the effect of ketamine/xylazine and pentobarbital anaesthesia on heart rate variability as a marker of autonomic nervous system activity. The experiments were performed in ketamine/xylazine (10 mg/kg/15 mg/kg) and pentobarbital (40 mg/kg, i.p.) anaesthetized female Wistar rats, after adaptation to a light-dark cycle of 12 hours light: 12 hours dark. Heart rate variability parameters (RR interval, power VLF (very low frequency), power LF (low frequency), power HF (high frequency) and relative powers) were evaluated during spontaneous breathing as a function of the light-dark cycle (LD cycle). Ketamine/xylazine anaesthesia increased parasympathetic activity, and suppressed sympathetic and baroreceptor activity independently of the light-dark cycle. Pentobarbital anaesthesia increased parasympathetic activity, decreased sympathetic and baroreceptor activity, and eliminated LD differences in RR interval duration.
dcterms:title
Autonomic nervous system under ketamine/ xylazine and pentobarbital anaesthesia in a Wistar rat model: a chronobiological view Autonomic nervous system under ketamine/ xylazine and pentobarbital anaesthesia in a Wistar rat model: a chronobiological view
skos:prefLabel
Autonomic nervous system under ketamine/ xylazine and pentobarbital anaesthesia in a Wistar rat model: a chronobiological view Autonomic nervous system under ketamine/ xylazine and pentobarbital anaesthesia in a Wistar rat model: a chronobiological view
skos:notation
RIV/61988987:17110/13:A140181Q!RIV14-MSM-17110___
n11:predkladatel
n17:orjk%3A17110
n3:aktivita
n18:I
n3:aktivity
I
n3:cisloPeriodika
2
n3:dodaniDat
n8:2014
n3:domaciTvurceVysledku
n9:4299434 n9:3419959
n3:druhVysledku
n14:J
n3:duvernostUdaju
n12:S
n3:entitaPredkladatele
n15:predkladatel
n3:idSjednocenehoVysledku
62688
n3:idVysledku
RIV/61988987:17110/13:A140181Q
n3:jazykVysledku
n4:eng
n3:klicovaSlova
Anaesthesia; Interval; Ketamine/xylazine; Pentobarbital; Rat; Heart rate variability
n3:klicoveSlovo
n5:Rat n5:Ketamine%2Fxylazine n5:Anaesthesia n5:Heart%20rate%20variability n5:Pentobarbital n5:Interval
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[6CDD13B4A980]
n3:nazevZdroje
Prague Medical Report
n3:obor
n16:FE
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
4
n3:rokUplatneniVysledku
n8:2013
n3:svazekPeriodika
114
n3:tvurceVysledku
Švorc, Pavol Bačová, I. Bužga, Marek Švorc, P.
s:issn
1214-6994
s:numberOfPages
9
n10:organizacniJednotka
17110