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Statements

Subject Item
n2:RIV%2F61988987%3A17110%2F08%3AA12014E9%21RIV12-MSM-17110___
rdf:type
skos:Concept n15:Vysledek
dcterms:description
Kaposi sarcoma (KS) has become a common manifestation in people with AIDS, especially men. The histology of Bohemian 71-old-year woman with nodul of spindle cell tumour expressing endothelial markers FVIII and Vimentin, CD31, CD34 markers were ob served. The disease is typically described in association with HHV-8 (human herpes virus-8) infection and several genetic abnormalities including gain of 8q and 1q, loss of 3p and 7q22, 8p11, 13q11 and 19q13 rearrangements. However, the data obtained from either earlier or later stages utilizing comparative genomic hybridisation remain controversial. Here, we show in our case monosomy of chromosome 17 utilizing FISH method on paraffin sections. Interestingly, we did not observe the previously reported aberrations of gain of 1q and 3q associated with diagnosed KS. In these report we present clinical, pathologic and laboratory findings in a case of unusual nodular form of KS which affected woman with HIV seronegative. Kaposi sarcoma (KS) has become a common manifestation in people with AIDS, especially men. The histology of Bohemian 71-old-year woman with nodul of spindle cell tumour expressing endothelial markers FVIII and Vimentin, CD31, CD34 markers were ob served. The disease is typically described in association with HHV-8 (human herpes virus-8) infection and several genetic abnormalities including gain of 8q and 1q, loss of 3p and 7q22, 8p11, 13q11 and 19q13 rearrangements. However, the data obtained from either earlier or later stages utilizing comparative genomic hybridisation remain controversial. Here, we show in our case monosomy of chromosome 17 utilizing FISH method on paraffin sections. Interestingly, we did not observe the previously reported aberrations of gain of 1q and 3q associated with diagnosed KS. In these report we present clinical, pathologic and laboratory findings in a case of unusual nodular form of KS which affected woman with HIV seronegative.
dcterms:title
An unusual variant of nodular form of Kaposi sarcoma An unusual variant of nodular form of Kaposi sarcoma
skos:prefLabel
An unusual variant of nodular form of Kaposi sarcoma An unusual variant of nodular form of Kaposi sarcoma
skos:notation
RIV/61988987:17110/08:A12014E9!RIV12-MSM-17110___
n3:aktivita
n13:N n13:V
n3:aktivity
N, V
n3:dodaniDat
n14:2012
n3:domaciTvurceVysledku
n16:2242184 n16:7095066 n16:4322509
n3:druhVysledku
n8:D
n3:duvernostUdaju
n17:S
n3:entitaPredkladatele
n18:predkladatel
n3:idSjednocenehoVysledku
355717
n3:idVysledku
RIV/61988987:17110/08:A12014E9
n3:jazykVysledku
n4:eng
n3:klicovaSlova
Kaposi sarcoma; HIV; human herpes virus; monosomy of chromosome; nodular
n3:klicoveSlovo
n6:human%20herpes%20virus n6:Kaposi%20sarcoma n6:HIV n6:monosomy%20of%20chromosome n6:nodular
n3:kontrolniKodProRIV
[B9B7DF22C582]
n3:mistoKonaniAkce
Barcelona, SPAIN
n3:mistoVydani
BOLOGNA, ITALY
n3:nazevZdroje
PROCEEDINGS OF THE 3RD INTERCONTINENTAL CONGRESS OF PATHOLOGY - FREE PAPERS
n3:obor
n7:FP
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
10
n3:rokUplatneniVysledku
n14:2008
n3:tvurceVysledku
Macháčková, A. Uvírová, Magdalena Tichá, V. Čeganová, L. Štěrba, J. Čegan, M. Žiak, Dušan Tichý, M. Čejka, P. Dvořáčková, Jana
n3:typAkce
n5:WRD
n3:wos
000257459300035
n3:zahajeniAkce
2008-05-17+02:00
s:numberOfPages
6
n19:hasPublisher
MEDIMOND S R L
n20:isbn
978-88-7587-447-6
n11:organizacniJednotka
17110