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Statements

Subject Item
n2:RIV%2F61988987%3A17110%2F05%3AA1000VS2%21RIV10-MSM-17110___
rdf:type
n3:Vysledek skos:Concept
dcterms:description
New-onset diabetes mellitus (NODM) is associated with increased risk of graft failure and death in renal transplant recipients. Some clinical studies have indicated that NODM risk is higher with tacrolimus than cyclosporine, but no comparative trial has used American Diabetic Association (ADA)/World Health Organization (WHO) criteria for diagnosis of diabetes mellitus. The Diabetes Incidence After Renal Transplantation, Neoral C-2 Monitoring Versus Tacrolimus (DIRECT) study is a 6-month open-label, multicenter trial comparing the impact of tacrolimus and Neoral (cyclosporine microemulsion) on glucose metabolism in 700 de novo kidney transplant recipients, based on ADA/WHO criteria. New-onset diabetes mellitus (NODM) is associated with increased risk of graft failure and death in renal transplant recipients. Some clinical studies have indicated that NODM risk is higher with tacrolimus than cyclosporine, but no comparative trial has used American Diabetic Association (ADA)/World Health Organization (WHO) criteria for diagnosis of diabetes mellitus. The Diabetes Incidence After Renal Transplantation, Neoral C-2 Monitoring Versus Tacrolimus (DIRECT) study is a 6-month open-label, multicenter trial comparing the impact of tacrolimus and Neoral (cyclosporine microemulsion) on glucose metabolism in 700 de novo kidney transplant recipients, based on ADA/WHO criteria.
dcterms:title
Prospective, multicenter, randomized trial to compare incidence of new-onset diabetes mellitus and glucose metabolism in patients receiving cyclosporine microemulsion versus tacrolimus after de novo kidney transplantation Prospective, multicenter, randomized trial to compare incidence of new-onset diabetes mellitus and glucose metabolism in patients receiving cyclosporine microemulsion versus tacrolimus after de novo kidney transplantation
skos:prefLabel
Prospective, multicenter, randomized trial to compare incidence of new-onset diabetes mellitus and glucose metabolism in patients receiving cyclosporine microemulsion versus tacrolimus after de novo kidney transplantation Prospective, multicenter, randomized trial to compare incidence of new-onset diabetes mellitus and glucose metabolism in patients receiving cyclosporine microemulsion versus tacrolimus after de novo kidney transplantation
skos:notation
RIV/61988987:17110/05:A1000VS2!RIV10-MSM-17110___
n4:aktivita
n6:N n6:S
n4:aktivity
N, S
n4:cisloPeriodika
2
n4:dodaniDat
n16:2010
n4:domaciTvurceVysledku
n10:3867781
n4:druhVysledku
n11:J
n4:duvernostUdaju
n17:S
n4:entitaPredkladatele
n12:predkladatel
n4:idSjednocenehoVysledku
539328
n4:idVysledku
RIV/61988987:17110/05:A1000VS2
n4:jazykVysledku
n13:eng
n4:klicovaSlova
RENAL-TRANSPLANTATION; UNITED-STATES; FK506
n4:klicoveSlovo
n5:UNITED-STATES n5:RENAL-TRANSPLANTATION n5:FK506
n4:kodStatuVydavatele
US - Spojené státy americké
n4:kontrolniKodProRIV
[D6CBC62345D8]
n4:nazevZdroje
TRANSPL P
n4:obor
n7:FE
n4:pocetDomacichTvurcuVysledku
1
n4:pocetTvurcuVysledku
1
n4:rokUplatneniVysledku
n16:2005
n4:svazekPeriodika
37
n4:tvurceVysledku
Martínek, Arnošt
n4:wos
000228568900156
s:issn
0041-1345
s:numberOfPages
5
n14:organizacniJednotka
17110