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Statements

Subject Item
n2:RIV%2F61389030%3A_____%2F12%3A00380690%21RIV13-AV0-61389030
rdf:type
n10:Vysledek skos:Concept
rdfs:seeAlso
http://brevets-patents.ic.gc.ca/opic-cipo/cpd/eng/patent/2524344/summary.html
dcterms:description
The invention relates to 3-, 7-disubstituted pyrazolo[4,3-d]pyrimidines represented by the general formula I (I), and pharmaceutically acceptable salts thereof, wherein R3 is selected from the group consisting of alkyl, cycloalkyl, , cycloalkyl alkyl, cycloheteroalkyl alkyl, cycloheteroalkyl, aryl, heterocycle, heteroaryl, arylalkyl, heteroarylalkyl, and heteroalkyl, wherein each of the groups may optionally be substituted, R7 is selected from the group consisting of halogen, hydroxyl, hydroxylamino, amino, carboxyl, cyano, nitro, amido, sulfo, sulfamido, carbamino, unsubstituted or substituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted heteroarylakyl, substituted or unsubstituted cycloalkyl alkyl, substituted or unsubstituted cycloheteroalkyl alkyl; R7'-X- wherein X is an - NH-, -N(alkyl)-, -0- or -S- moiety and R7' is selected from the group consisting of H, alkyl, cycloalkyl, aryl, alkylcycloalkyl, arylalkyl, heterocycle, heterocyclealkyl, substituted alkyl, substituted cycloalkyl, substituted aryl, substituted arylalkyl, substituted heterocycle, substituted heteroaryl, substituted heteroarylalkyl, substituted heteroalkyl, substituted cycloalkyl alkyl and substituted cycloheteroalkyl alkyl, wherein the groups are preferably substituted by more than one halogen, hydroxyl, amino, mercapto, carboxyl, cyano, nitro, amido, sulfo, sulfamido, carbamino, alkyl, alkoxy, and substituted alkyl group. The invention relates to 3-, 7-disubstituted pyrazolo[4,3-d]pyrimidines represented by the general formula I (I), and pharmaceutically acceptable salts thereof, wherein R3 is selected from the group consisting of alkyl, cycloalkyl, , cycloalkyl alkyl, cycloheteroalkyl alkyl, cycloheteroalkyl, aryl, heterocycle, heteroaryl, arylalkyl, heteroarylalkyl, and heteroalkyl, wherein each of the groups may optionally be substituted, R7 is selected from the group consisting of halogen, hydroxyl, hydroxylamino, amino, carboxyl, cyano, nitro, amido, sulfo, sulfamido, carbamino, unsubstituted or substituted alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted heteroarylakyl, substituted or unsubstituted cycloalkyl alkyl, substituted or unsubstituted cycloheteroalkyl alkyl; R7'-X- wherein X is an - NH-, -N(alkyl)-, -0- or -S- moiety and R7' is selected from the group consisting of H, alkyl, cycloalkyl, aryl, alkylcycloalkyl, arylalkyl, heterocycle, heterocyclealkyl, substituted alkyl, substituted cycloalkyl, substituted aryl, substituted arylalkyl, substituted heterocycle, substituted heteroaryl, substituted heteroarylalkyl, substituted heteroalkyl, substituted cycloalkyl alkyl and substituted cycloheteroalkyl alkyl, wherein the groups are preferably substituted by more than one halogen, hydroxyl, amino, mercapto, carboxyl, cyano, nitro, amido, sulfo, sulfamido, carbamino, alkyl, alkoxy, and substituted alkyl group.
dcterms:title
Pyrazolo[4,3-D]pyrimidines, process for their preparation and methods of use Pyrazolo[4,3-D]pyrimidines, process for their preparation and methods of use
skos:prefLabel
Pyrazolo[4,3-D]pyrimidines, process for their preparation and methods of use Pyrazolo[4,3-D]pyrimidines, process for their preparation and methods of use
skos:notation
RIV/61389030:_____/12:00380690!RIV13-AV0-61389030
n10:predkladatel
n23:ico%3A61389030
n4:aktivita
n13:P n13:Z
n4:aktivity
P(GA301/08/1649), Z(AV0Z50380511)
n4:cisloPatentuVzoru
CA2524344
n4:datumUdeleniPatentuVzoru
2012-03-13+01:00
n4:dodaniDat
n17:2013
n4:domaciTvurceVysledku
n8:9130241 n8:4712048 n8:9896821 n8:9961216 n8:1870378 n8:6282520
n4:druhVysledku
n12:P
n4:duvernostUdaju
n24:S
n4:entitaPredkladatele
n6:predkladatel
n4:idSjednocenehoVysledku
163690
n4:idVysledku
RIV/61389030:_____/12:00380690
n4:jazykVysledku
n18:eng
n4:klicovaSlova
Pyrazolo[4,3-D]pyrimidines; preparation; methods of use
n4:klicoveSlovo
n7:preparation n7:Pyrazolo%5B4 n7:methods%20of%20use n7:3-D%5Dpyrimidines
n4:kontrolniKodProRIV
[EE5C2BBC1FA5]
n4:licencniPoplatek
n22:A
n4:mistoVydaniPatentuVzoru
Gatineau, Québec
n4:nazevVydavatelePatentuVzoru
Canadian Intellectual Property Office (CIPO)
n4:obor
n16:CE
n4:pocetDomacichTvurcuVysledku
6
n4:pocetTvurcuVysledku
10
n4:projekt
n20:GA301%2F08%2F1649
n4:rokUplatneniVysledku
n17:2012
n4:statVydaniPatentuVzoru
n11:CA
n4:tvurceVysledku
Mlejnek, P. Kryštof, Vladimír Vojtěšek, B. Strnad, Miroslav Lenobel, René Moravcová, Daniela Schmülling, T. Uldrijan, S. Havlíček, Libor Binarová, Pavla
n4:uzemniOchranaPatentu
n15:D
n4:vlastnik
n6:vlastnikVysledku
n4:vyuzitiJinymSubjektem
n21:A
n4:vyuzitiPatentuVzoru
n14:B
n4:zamer
n19:AV0Z50380511
n4:vlastnikPatentuVzoru
Ústav experimentální botaniky AV ČR, v. v. i - Univerzita Palackého v Olomouci