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Statements

Subject Item
n2:RIV%2F61389030%3A_____%2F03%3A56033102%21RIV%2F2004%2FGA0%2FA56004%2FN
rdf:type
n15:Vysledek skos:Concept
dcterms:description
A search among analogues of anti-CDK purines led to the identification of substituted pyrazolo[4,3-d]pyrimidines as novel inhibitors of CDK1/cyclin B. Some of these derivatives also show antiproliferative activity on cancer cell line K-562, thus may find an application as anticancer agents. A search among analogues of anti-CDK purines led to the identification of substituted pyrazolo[4,3-d]pyrimidines as novel inhibitors of CDK1/cyclin B. Some of these derivatives also show antiproliferative activity on cancer cell line K-562, thus may find an application as anticancer agents.
dcterms:title
Pyrazolo[4,3-d]pyrimidines as new generation of cyclin-dependent kinase inhibitors. Pyrazolo[4,3-d]pyrimidines as new generation of cyclin-dependent kinase inhibitors.
skos:prefLabel
Pyrazolo[4,3-d]pyrimidines as new generation of cyclin-dependent kinase inhibitors. Pyrazolo[4,3-d]pyrimidines as new generation of cyclin-dependent kinase inhibitors.
skos:notation
RIV/61389030:_____/03:56033102!RIV/2004/GA0/A56004/N
n3:strany
2989ů2992
n3:aktivita
n5:Z n5:P
n3:aktivity
P(GA301/02/0475), P(GA303/02/0875), P(KJB4038301), Z(AV0Z5038910)
n3:cisloPeriodika
18
n3:dodaniDat
n14:2004
n3:domaciTvurceVysledku
n9:4712048 n9:7310188 n9:9130241 n9:1870378 n9:9896821 n9:9961216
n3:druhVysledku
n17:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n4:predkladatel
n3:idSjednocenehoVysledku
624326
n3:idVysledku
RIV/61389030:_____/03:56033102
n3:jazykVysledku
n12:eng
n3:klicovaSlova
Pyrazolo[4,3-d]pyrimidines; CDK1/cyclin B; anticancer agents
n3:klicoveSlovo
n6:3-d%5Dpyrimidines n6:Pyrazolo%5B4 n6:anticancer%20agents n6:CDK1%2Fcyclin%20B
n3:kodStatuVydavatele
NL - Nizozemsko
n3:kontrolniKodProRIV
[7174171FFBD1]
n3:nazevZdroje
Bioorganic and Medicinal Chemistry Letters
n3:obor
n8:EB
n3:pocetDomacichTvurcuVysledku
6
n3:pocetTvurcuVysledku
6
n3:pocetUcastnikuAkce
0
n3:pocetZahranicnichUcastnikuAkce
0
n3:projekt
n10:GA303%2F02%2F0875 n10:KJB4038301 n10:GA301%2F02%2F0475
n3:rokUplatneniVysledku
n14:2003
n3:svazekPeriodika
13
n3:tvurceVysledku
Strnad, Miroslav Moravec, Jiří Havlíček, Libor Moravcová, Daniela Kryštof, Vladimír Lenobel, René
n3:zamer
n16:AV0Z5038910
s:issn
0960-894X
s:numberOfPages
4