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Statements

Subject Item
n2:RIV%2F61389030%3A_____%2F02%3A56023003%21RIV%2F2003%2FAV0%2FA56003%2FN
rdf:type
n8:Vysledek skos:Concept
dcterms:description
Synthetic oligopeptides, tri- to pentaglycine and tri- and tetraalanine, were found to enhance viable cell density and culture viability when applied at concentrations higher than milllimolar to the cultures of a model hybridoma line. Oligoalanines, in addition, enhanced monoclonal antibody yields. Oligoglycines promoted solely the cell growth, unless the batch culture was fed with a medium concentrate. Examination of the effects of various tripeptides composed of glycine, alanine, serine, threonine, lysine, and histidine showed that some of the peptides promoted the growth of the culture, while other peptides suppressed the growth and enhanced the monoclonal antibody yield. Synthetic oligopeptides, tri- to pentaglycine and tri- and tetraalanine, were found to enhance viable cell density and culture viability when applied at concentrations higher than milllimolar to the cultures of a model hybridoma line. Oligoalanines, in addition, enhanced monoclonal antibody yields. Oligoglycines promoted solely the cell growth, unless the batch culture was fed with a medium concentrate. Examination of the effects of various tripeptides composed of glycine, alanine, serine, threonine, lysine, and histidine showed that some of the peptides promoted the growth of the culture, while other peptides suppressed the growth and enhanced the monoclonal antibody yield.
dcterms:title
Specific Effects of Synthetic Oligopeptides on Cultured Animal Cells. Specific Effects of Synthetic Oligopeptides on Cultured Animal Cells.
skos:prefLabel
Specific Effects of Synthetic Oligopeptides on Cultured Animal Cells. Specific Effects of Synthetic Oligopeptides on Cultured Animal Cells.
skos:notation
RIV/61389030:_____/02:56023003!RIV/2003/AV0/A56003/N
n3:strany
155;158
n3:aktivita
n4:P n4:Z
n3:aktivity
P(OC 844.10), Z(AV0Z5038910)
n3:cisloPeriodika
N/A
n3:dodaniDat
n7:2003
n3:domaciTvurceVysledku
n10:5671140
n3:druhVysledku
n18:J
n3:duvernostUdaju
n15:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
664493
n3:idVysledku
RIV/61389030:_____/02:56023003
n3:jazykVysledku
n9:eng
n3:klicovaSlova
Oligopeptides; Animal Cells
n3:klicoveSlovo
n5:Oligopeptides n5:Animal%20Cells
n3:kodStatuVydavatele
AT - Rakouská republika
n3:kontrolniKodProRIV
[97ED456C9606]
n3:nazevZdroje
Biotechnology Progress
n3:obor
n17:CE
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
2
n3:pocetUcastnikuAkce
0
n3:pocetZahranicnichUcastnikuAkce
0
n3:projekt
n13:OC%20844.10
n3:rokUplatneniVysledku
n7:2002
n3:svazekPeriodika
18
n3:tvurceVysledku
Katinger, H. Franěk, František
n3:zamer
n14:AV0Z5038910
s:issn
8756-7938
s:numberOfPages
4