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Statements

Subject Item
n2:RIV%2F61389021%3A_____%2F12%3A00386673%21RIV13-GA0-61389021
rdf:type
skos:Concept n13:Vysledek
dcterms:description
Předneseno na: 28th International Symposium on Shock Waves, Manchester, GB, 17.07.-22.07.2011,str. 839-845: Physical principles of novel type of generator of focused tandem shock waves with time delay between the first and second shock waves of 10 µs have been presented. Generator produces at the focus strong shock wave with peak positive pressure up to 80 MPa followed by tensile wave with peak negative pressure down up to -80 MPa, generating thus at the focus a large number of cavitation. Biological effects of FTSW were demonstrated in vitro on hemolysis of erythrocytes and cell viability of acute lymphoblastic leukemia cells, and on tumor growth delay experiments ex vivo and in vivo. Synergetic cytotoxicity of FTSW with Photosan on tumor growth was observed, possibly due to cavitation induced sonodynamic effect of FTSW. Předneseno na: 28th International Symposium on Shock Waves, Manchester, GB, 17.07.-22.07.2011,str. 839-845: Physical principles of novel type of generator of focused tandem shock waves with time delay between the first and second shock waves of 10 µs have been presented. Generator produces at the focus strong shock wave with peak positive pressure up to 80 MPa followed by tensile wave with peak negative pressure down up to -80 MPa, generating thus at the focus a large number of cavitation. Biological effects of FTSW were demonstrated in vitro on hemolysis of erythrocytes and cell viability of acute lymphoblastic leukemia cells, and on tumor growth delay experiments ex vivo and in vivo. Synergetic cytotoxicity of FTSW with Photosan on tumor growth was observed, possibly due to cavitation induced sonodynamic effect of FTSW.
dcterms:title
Focused tandem shock waves in water and their potential application in cancer treatment Focused tandem shock waves in water and their potential application in cancer treatment
skos:prefLabel
Focused tandem shock waves in water and their potential application in cancer treatment Focused tandem shock waves in water and their potential application in cancer treatment
skos:notation
RIV/61389021:_____/12:00386673!RIV13-GA0-61389021
n13:predkladatel
n14:ico%3A61389021
n3:aktivita
n11:Z n11:P
n3:aktivity
P(GA202/09/1151), Z(AV0Z20430508)
n3:dodaniDat
n5:2013
n3:domaciTvurceVysledku
n10:8384908 n10:4439678 Stelmashuk, Vitaliy n10:5008824
n3:druhVysledku
n17:C
n3:duvernostUdaju
n8:S
n3:entitaPredkladatele
n12:predkladatel
n3:idSjednocenehoVysledku
136882
n3:idVysledku
RIV/61389021:_____/12:00386673
n3:jazykVysledku
n20:eng
n3:klicovaSlova
focused shock waves; underwater discharge; cancer treatment
n3:klicoveSlovo
n9:underwater%20discharge n9:focused%20shock%20waves n9:cancer%20treatment
n3:kontrolniKodProRIV
[DF0F21D0E85A]
n3:mistoVydani
Berlin Heidelberg
n3:nazevZdroje
28th International Symposium on Shock Waves
n3:obor
n6:BL
n3:pocetDomacichTvurcuVysledku
4
n3:pocetStranKnihy
1121
n3:pocetTvurcuVysledku
12
n3:projekt
n15:GA202%2F09%2F1151
n3:rokUplatneniVysledku
n5:2012
n3:tvurceVysledku
Dibdiak, L. Stelmashuk, Vitaliy Šunka, Pavel Binder, S. Hoffer, Petr Zeman, J. Beneš, J. Kolářová, H. Zadinová, M. Tománková, K. Lukeš, Petr Poučková, P.
n3:zamer
n21:AV0Z20430508
s:numberOfPages
7
n19:doi
10.1007/978-3-642-25685-1
n22:hasPublisher
Springer Verlag GmbH
n16:isbn
978-3-642-25684-4