This HTML5 document contains 51 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n11http://linked.opendata.cz/resource/domain/vavai/projekt/
n6http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n16http://linked.opendata.cz/resource/domain/vavai/subjekt/
n13http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F61389013%3A_____%2F13%3A00383512%21RIV13-AV0-61389013/
n7http://linked.opendata.cz/ontology/domain/vavai/
n10http://linked.opendata.cz/resource/domain/vavai/zamer/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
n5http://linked.opendata.cz/ontology/domain/vavai/riv/
n14http://bibframe.org/vocab/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n19http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n18http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n15http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n8http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n20http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n12http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n17http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F61389013%3A_____%2F13%3A00383512%21RIV13-AV0-61389013
rdf:type
n7:Vysledek skos:Concept
dcterms:description
In this contribution the ability of 19F MAS NMR spectroscopy to probe structural variability of poorly water-soluble drugs formulated as solid dispersions in polymer matrices is discussed. The application potentiality of the proposed approach is demonstrated on a moderately sized active pharmaceutical ingredient (API, Atorvastatin) exhibiting extensive polymorphism. In this respect, a range of model systems with the API incorporated in the matrix of polvinylpyrrolidone (PVP) was prepared. In this contribution the ability of 19F MAS NMR spectroscopy to probe structural variability of poorly water-soluble drugs formulated as solid dispersions in polymer matrices is discussed. The application potentiality of the proposed approach is demonstrated on a moderately sized active pharmaceutical ingredient (API, Atorvastatin) exhibiting extensive polymorphism. In this respect, a range of model systems with the API incorporated in the matrix of polvinylpyrrolidone (PVP) was prepared.
dcterms:title
Characterization of solid polymer dispersions of active pharmaceutical ingredients by 19F MAS NMR and factor analysis Characterization of solid polymer dispersions of active pharmaceutical ingredients by 19F MAS NMR and factor analysis
skos:prefLabel
Characterization of solid polymer dispersions of active pharmaceutical ingredients by 19F MAS NMR and factor analysis Characterization of solid polymer dispersions of active pharmaceutical ingredients by 19F MAS NMR and factor analysis
skos:notation
RIV/61389013:_____/13:00383512!RIV13-AV0-61389013
n7:predkladatel
n16:ico%3A61389013
n5:aktivita
n8:P n8:I n8:Z
n5:aktivity
I, P(2B08021), P(GPP106/11/P426), Z(AV0Z40500505)
n5:cisloPeriodika
1 January
n5:dodaniDat
n17:2013
n5:domaciTvurceVysledku
n6:5021197 n6:5887852 n6:6500579 n6:2613549 n6:6354068
n5:druhVysledku
n20:J
n5:duvernostUdaju
n18:S
n5:entitaPredkladatele
n13:predkladatel
n5:idSjednocenehoVysledku
65100
n5:idVysledku
RIV/61389013:_____/13:00383512
n5:jazykVysledku
n15:eng
n5:klicovaSlova
solid-state NMR; factor analysis; 19F MAS NMR
n5:klicoveSlovo
n19:19F%20MAS%20NMR n19:factor%20analysis n19:solid-state%20NMR
n5:kodStatuVydavatele
NL - Nizozemsko
n5:kontrolniKodProRIV
[4DF8D81105F2]
n5:nazevZdroje
Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy
n5:obor
n12:FR
n5:pocetDomacichTvurcuVysledku
5
n5:pocetTvurcuVysledku
5
n5:projekt
n11:GPP106%2F11%2FP426 n11:2B08021
n5:rokUplatneniVysledku
n17:2013
n5:svazekPeriodika
100
n5:tvurceVysledku
Brus, Jiří Šeděnková, Ivana Kobera, Libor Policianová, Olivia Urbanová, Martina
n5:wos
000312181800009
n5:zamer
n10:AV0Z40500505
s:issn
1386-1425
s:numberOfPages
8
n14:doi
10.1016/j.saa.2012.02.057