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Statements

Subject Item
n2:RIV%2F61388971%3A_____%2F14%3A00435255%21RIV15-AV0-61388971
rdf:type
n11:Vysledek skos:Concept
dcterms:description
Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) belong to the group of persistent organic pollutants, highly toxic environmental pollutants that include hydrophobic compounds with the tendency to bioaccumulate. Earthworms (Eisenia andrei) were exposed to PCDD/Fs-contaminated soil, and changes in their lipophilic structures and the gene expression of their defense molecules were followed. Damage to the intestinal wall and adjacent chloragogenous tissue was observed. Further, the up-regulation of the expression of several genes was detected. On the basis of these results, the mechanism of the impact of PCDD/Fs on earthworms has been proposed. Dioxins that accumulate in the lipophilic structures cause an increase in reactive oxidative species that triggers oxidative stress followed by the gene expression of two molecules that play a role in protection against oxidant toxicity, calreticulin (CRT) and Hsp70. Moreover, the effect of microbial biomass on the expression of coelomic cytolytic factor (CCF), a pattern recognition receptor, was also observed. Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) belong to the group of persistent organic pollutants, highly toxic environmental pollutants that include hydrophobic compounds with the tendency to bioaccumulate. Earthworms (Eisenia andrei) were exposed to PCDD/Fs-contaminated soil, and changes in their lipophilic structures and the gene expression of their defense molecules were followed. Damage to the intestinal wall and adjacent chloragogenous tissue was observed. Further, the up-regulation of the expression of several genes was detected. On the basis of these results, the mechanism of the impact of PCDD/Fs on earthworms has been proposed. Dioxins that accumulate in the lipophilic structures cause an increase in reactive oxidative species that triggers oxidative stress followed by the gene expression of two molecules that play a role in protection against oxidant toxicity, calreticulin (CRT) and Hsp70. Moreover, the effect of microbial biomass on the expression of coelomic cytolytic factor (CCF), a pattern recognition receptor, was also observed.
dcterms:title
The effect of dibenzo-p-dioxin- and dibenzofuran-contaminated soil on the earthworm Eisenia andrei The effect of dibenzo-p-dioxin- and dibenzofuran-contaminated soil on the earthworm Eisenia andrei
skos:prefLabel
The effect of dibenzo-p-dioxin- and dibenzofuran-contaminated soil on the earthworm Eisenia andrei The effect of dibenzo-p-dioxin- and dibenzofuran-contaminated soil on the earthworm Eisenia andrei
skos:notation
RIV/61388971:_____/14:00435255!RIV15-AV0-61388971
n3:aktivita
n17:P n17:I
n3:aktivity
I, P(ED1.1.00/02.0109), P(EE2.3.20.0055), P(EE2.3.30.0003)
n3:cisloPeriodika
OCT 2014
n3:dodaniDat
n12:2015
n3:domaciTvurceVysledku
n9:4991974 n9:8721386 n9:5013984 n9:5842573 n9:2020017 n9:6562256
n3:druhVysledku
n15:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
13224
n3:idVysledku
RIV/61388971:_____/14:00435255
n3:jazykVysledku
n14:eng
n3:klicovaSlova
Eisenia andrei; PCDD/Fs; Calreticulin
n3:klicoveSlovo
n8:PCDD%2FFs n8:Eisenia%20andrei n8:Calreticulin
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[52F9DD129AB6]
n3:nazevZdroje
Environmental Pollution
n3:obor
n5:EE
n3:pocetDomacichTvurcuVysledku
6
n3:pocetTvurcuVysledku
7
n3:projekt
n6:ED1.1.00%2F02.0109 n6:EE2.3.20.0055 n6:EE2.3.30.0003
n3:rokUplatneniVysledku
n12:2014
n3:svazekPeriodika
193
n3:tvurceVysledku
Škanta, František Rossmann, Pavel Procházková, Petra Dvořák, Jiří Bilej, Martin Elhottová, Dana Roubalová, Radka
n3:wos
000341471300004
s:issn
0269-7491
s:numberOfPages
7
n7:doi
10.1016/j.envpol.2014.05.026