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Statements

Subject Item
n2:RIV%2F61388971%3A_____%2F11%3A00366242%21RIV12-AV0-61388971
rdf:type
skos:Concept n17:Vysledek
dcterms:description
Poly-N-acetyllactosamine (Poly-LacNAc, [3Galβ1,4GlcNAcβ1]n) glycans play an Essentials role in carbohydrate-protein interactions. The synthesis of poly-LacNAc, both chemical and enzymatic, is typically characterized by high losses of product during sequential synthesis, due to deprotection and/ or purification steps. In this work we present a onepot synthesis of poly-LacNAc oligosaccharides by combining recombinant glycosyltransferases Poly-N-acetyllactosamine (Poly-LacNAc, [3Galβ1,4GlcNAcβ1]n) glycans play an Essentials role in carbohydrate-protein interactions. The synthesis of poly-LacNAc, both chemical and enzymatic, is typically characterized by high losses of product during sequential synthesis, due to deprotection and/ or purification steps. In this work we present a onepot synthesis of poly-LacNAc oligosaccharides by combining recombinant glycosyltransferases
dcterms:title
Combinatorial One-Pot Synthesis of Poly-N-acetyllactosamine Oligosaccharides with Leloir-Glycosyltransferases Combinatorial One-Pot Synthesis of Poly-N-acetyllactosamine Oligosaccharides with Leloir-Glycosyltransferases
skos:prefLabel
Combinatorial One-Pot Synthesis of Poly-N-acetyllactosamine Oligosaccharides with Leloir-Glycosyltransferases Combinatorial One-Pot Synthesis of Poly-N-acetyllactosamine Oligosaccharides with Leloir-Glycosyltransferases
skos:notation
RIV/61388971:_____/11:00366242!RIV12-AV0-61388971
n17:predkladatel
n18:ico%3A61388971
n4:aktivita
n7:P n7:Z
n4:aktivity
P(OC09045), Z(AV0Z50200510)
n4:cisloPeriodika
13
n4:dodaniDat
n8:2012
n4:domaciTvurceVysledku
n12:7346689 n12:5894190 n12:3895831 n12:7203993
n4:druhVysledku
n20:J
n4:duvernostUdaju
n15:S
n4:entitaPredkladatele
n6:predkladatel
n4:idSjednocenehoVysledku
190872
n4:idVysledku
RIV/61388971:_____/11:00366242
n4:jazykVysledku
n19:eng
n4:klicovaSlova
combinatorial chemistry; biocatalysis; carbohydrates
n4:klicoveSlovo
n10:biocatalysis n10:carbohydrates n10:combinatorial%20chemistry
n4:kodStatuVydavatele
DE - Spolková republika Německo
n4:kontrolniKodProRIV
[754838EC01BE]
n4:nazevZdroje
Advanced Synthesis & Catalysis
n4:obor
n11:CC
n4:pocetDomacichTvurcuVysledku
4
n4:pocetTvurcuVysledku
9
n4:projekt
n9:OC09045
n4:rokUplatneniVysledku
n8:2011
n4:svazekPeriodika
353
n4:tvurceVysledku
Rosencrantz, R. R. Rech, C. Pelantová, Helena Roemer, Ch. E. Bojarová, Pavla Křen, Vladimír Elling, L. Křenek, Karel Hanisch, F.-G.
n4:wos
000295230900028
n4:zamer
n14:AV0Z50200510
s:issn
1615-4150
s:numberOfPages
9
n16:doi
10.1002/adsc.201100375