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Statements

Subject Item
n2:RIV%2F61388971%3A_____%2F09%3A00328368%21RIV10-MZ0-61388971
rdf:type
skos:Concept n7:Vysledek
dcterms:description
The proteins of 14-3-3 family are substantially involved in the regulation of many biological processes including the apoptosis. We studied the changes in the expression of five 14-3-3 isoforms during the apoptosis of JURL-MK1 and K562 cells. The expression level of all these proteins markedly decreased in relation with the apoptosis progression and all isoforms underwent truncation, which probably corresponds to the removal of several C-terminal amino acids. The observed 14-3-3 modifications were partially blocked by caspase-3 inhibition The proteins of 14-3-3 family are substantially involved in the regulation of many biological processes including the apoptosis. We studied the changes in the expression of five 14-3-3 isoforms during the apoptosis of JURL-MK1 and K562 cells. The expression level of all these proteins markedly decreased in relation with the apoptosis progression and all isoforms underwent truncation, which probably corresponds to the removal of several C-terminal amino acids. The observed 14-3-3 modifications were partially blocked by caspase-3 inhibition
dcterms:title
Isoform-Specific Cleavage of 14-3-3 Proteins in Apoptotic JURL-MK1 Cells Isoform-Specific Cleavage of 14-3-3 Proteins in Apoptotic JURL-MK1 Cells
skos:prefLabel
Isoform-Specific Cleavage of 14-3-3 Proteins in Apoptotic JURL-MK1 Cells Isoform-Specific Cleavage of 14-3-3 Proteins in Apoptotic JURL-MK1 Cells
skos:notation
RIV/61388971:_____/09:00328368!RIV10-MZ0-61388971
n3:aktivita
n11:Z n11:P
n3:aktivity
P(NR9243), Z(AV0Z50200510)
n3:cisloPeriodika
4
n3:dodaniDat
n4:2010
n3:domaciTvurceVysledku
n8:8652406 n8:2185148
n3:druhVysledku
n17:J
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n18:predkladatel
n3:idSjednocenehoVysledku
320495
n3:idVysledku
RIV/61388971:_____/09:00328368
n3:jazykVysledku
n16:eng
n3:klicovaSlova
k562; apoptosis; 14-3-3
n3:klicoveSlovo
n6:k562 n6:apoptosis n6:14-3-3
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[99F1707088F3]
n3:nazevZdroje
Journal of Cellular Biochemistry
n3:obor
n12:CE
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
6
n3:projekt
n15:NR9243
n3:rokUplatneniVysledku
n4:2009
n3:svazekPeriodika
106
n3:tvurceVysledku
Kuželová, K. Halada, Petr Grebeňová, D. Hrkal, Z. Pluskalová, M. Kavan, Daniel
n3:wos
00026445630002
n3:zamer
n10:AV0Z50200510
s:issn
0730-2312
s:numberOfPages
9