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Statements

Subject Item
n2:RIV%2F61388963%3A_____%2F12%3A00376300%21RIV13-AV0-61388963
rdf:type
n11:Vysledek skos:Concept
dcterms:description
To determine the influence of internucleotide linkage and sugar ring conformation, and the role of 5'-terminal phosphate, on the activation of human RNase L, a series of 2'- and 5'-O-methylphosphonate-modified tetramers were synthesized from appropriate monomeric units and evaluated for their ability to activate human RNase L. To determine the influence of internucleotide linkage and sugar ring conformation, and the role of 5'-terminal phosphate, on the activation of human RNase L, a series of 2'- and 5'-O-methylphosphonate-modified tetramers were synthesized from appropriate monomeric units and evaluated for their ability to activate human RNase L.
dcterms:title
Activation of human RNase L by 2'- and 5'-O-methylphosphonate-modified olygoadenylates Activation of human RNase L by 2'- and 5'-O-methylphosphonate-modified olygoadenylates
skos:prefLabel
Activation of human RNase L by 2'- and 5'-O-methylphosphonate-modified olygoadenylates Activation of human RNase L by 2'- and 5'-O-methylphosphonate-modified olygoadenylates
skos:notation
RIV/61388963:_____/12:00376300!RIV13-AV0-61388963
n11:predkladatel
n15:ico%3A61388963
n3:aktivita
n14:Z n14:P
n3:aktivity
P(GA202/09/0193), P(KAN200520801), P(LC06061), Z(AV0Z40550506)
n3:cisloPeriodika
1
n3:dodaniDat
n7:2013
n3:domaciTvurceVysledku
n9:4235010 n9:9241299 n9:8160961 n9:4342771 Panova, Natalya
n3:druhVysledku
n17:J
n3:duvernostUdaju
n12:S
n3:entitaPredkladatele
n8:predkladatel
n3:idSjednocenehoVysledku
120946
n3:idVysledku
RIV/61388963:_____/12:00376300
n3:jazykVysledku
n18:eng
n3:klicovaSlova
RNase L; phosphonate; oligoadenylate
n3:klicoveSlovo
n10:RNase%20L n10:phosphonate n10:oligoadenylate
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[DED1800DEC98]
n3:nazevZdroje
Bioorganic and Medicinal Chemistry Letters
n3:obor
n20:CC
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
5
n3:projekt
n4:LC06061 n4:KAN200520801 n4:GA202%2F09%2F0193
n3:rokUplatneniVysledku
n7:2012
n3:svazekPeriodika
22
n3:tvurceVysledku
Snášel, Jan Páv, Ondřej Panova, Natalya Rosenberg, Ivan Zborníková, Eva
n3:wos
000298636700030
n3:zamer
n19:AV0Z40550506
s:issn
0960-894X
s:numberOfPages
5
n16:doi
10.1016/j.bmcl.2011.11.040