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Statements

Subject Item
n2:RIV%2F61388963%3A_____%2F10%3A00342386%21RIV11-GA0-61388963
rdf:type
n12:Vysledek skos:Concept
dcterms:description
In the present work we focus on the contribution of NC to the oligomerization of CA leading to assembly of Mason-Pfizer monkey virus (M-PMV) and HIV-1. Analyzing in vitro assembly of substitution and deletion mutants of .delta.ProCANC we identified a “spacer-like sequence (NC15) at the M-PMV NC N-terminus. This NC15 domain is indispensable for the assembly and cannot be substituted with oligomerization domains of GCN4 or CREB proteins. In the present work we focus on the contribution of NC to the oligomerization of CA leading to assembly of Mason-Pfizer monkey virus (M-PMV) and HIV-1. Analyzing in vitro assembly of substitution and deletion mutants of .delta.ProCANC we identified a “spacer-like sequence (NC15) at the M-PMV NC N-terminus. This NC15 domain is indispensable for the assembly and cannot be substituted with oligomerization domains of GCN4 or CREB proteins.
dcterms:title
The effect of dimerizing domains and basic residues on in vitro and in vivo assembly of Mason-Pfizer monkey virus and Human immunodeficiency virus The effect of dimerizing domains and basic residues on in vitro and in vivo assembly of Mason-Pfizer monkey virus and Human immunodeficiency virus
skos:prefLabel
The effect of dimerizing domains and basic residues on in vitro and in vivo assembly of Mason-Pfizer monkey virus and Human immunodeficiency virus The effect of dimerizing domains and basic residues on in vitro and in vivo assembly of Mason-Pfizer monkey virus and Human immunodeficiency virus
skos:notation
RIV/61388963:_____/10:00342386!RIV11-GA0-61388963
n3:aktivita
n14:Z n14:P
n3:aktivity
P(1M0508), P(GA204/09/1388), P(ME 904), Z(AV0Z40550506), Z(MSM6046137305)
n3:cisloPeriodika
4
n3:dodaniDat
n8:2011
n3:domaciTvurceVysledku
n9:4180178 n9:2264102 n9:7526105 n9:8571635 n9:5357985
n3:druhVysledku
n16:J
n3:duvernostUdaju
n13:S
n3:entitaPredkladatele
n17:predkladatel
n3:idSjednocenehoVysledku
255952
n3:idVysledku
RIV/61388963:_____/10:00342386
n3:jazykVysledku
n15:eng
n3:klicovaSlova
Mason-Pfizer Monkey Virus; Human Immunodeficiency Virus; assembly; NC
n3:klicoveSlovo
n7:NC n7:Mason-Pfizer%20Monkey%20Virus n7:assembly n7:Human%20Immunodeficiency%20Virus
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[2617C944F3A7]
n3:nazevZdroje
Journal of Virology
n3:obor
n18:CC
n3:pocetDomacichTvurcuVysledku
5
n3:pocetTvurcuVysledku
7
n3:projekt
n11:1M0508 n11:ME%20904 n11:GA204%2F09%2F1388
n3:rokUplatneniVysledku
n8:2010
n3:svazekPeriodika
84
n3:tvurceVysledku
Böhmová, Karolína Rumlová, Michaela Štokrová, Jitka Tůma, R. Ruml, T. Hadravová, Romana Pichová, Iva
n3:wos
000273853200032
n3:zamer
n4:AV0Z40550506 n4:MSM6046137305
s:issn
0022-538X
s:numberOfPages
12