This HTML5 document contains 52 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n18http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n7http://linked.opendata.cz/resource/domain/vavai/projekt/
n5http://linked.opendata.cz/ontology/domain/vavai/
n12http://linked.opendata.cz/resource/domain/vavai/zamer/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n10http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F61388963%3A_____%2F08%3A00316278%21RIV09-AV0-61388963/
n14http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n15http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n16http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n8http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n17http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n6http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n11http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F61388963%3A_____%2F08%3A00316278%21RIV09-AV0-61388963
rdf:type
n5:Vysledek skos:Concept
dcterms:description
The Candida antigen CR3-RP (complement receptor 3-related protein) was identified and characterized as a 'mimicry' protein, which might play a role in the adherence of Candida albicans. Blocking CR3-RP with polyclonal anti-CR3-RP serum reduced the ability of Candida to adhere to buccal epithelial cells and formation of biofilm by 28% (P,0.001), including changes in biofilm thickness and integrity detected by confocal laser scanning microscopy. These properties of CR3-RP suggest that it has potential for future vaccine development. The Candida antigen CR3-RP (complement receptor 3-related protein) was identified and characterized as a 'mimicry' protein, which might play a role in the adherence of Candida albicans. Blocking CR3-RP with polyclonal anti-CR3-RP serum reduced the ability of Candida to adhere to buccal epithelial cells and formation of biofilm by 28% (P,0.001), including changes in biofilm thickness and integrity detected by confocal laser scanning microscopy. These properties of CR3-RP suggest that it has potential for future vaccine development. Byl identifikován protein CR3-RP (protein podobný CR3 adhéznímu receptoru) u C. albicans. Blokování tohoto proteinu polyklonálními protilátkami snížilo schopnost C. albicans adherovat k bukálním epiteliálním buňkám a ovlivnilo tvorbu a tloušťku biofilmu, pozorovanou skenovacím konfokálním mikroskopem. Tyto výsledky ukazují, že CR3-RP by mohl sloužit pro vývoj vakcíny.
dcterms:title
Antibody response to the 45 kDa Candida albicans antigen in an animal model and potential role of the antigen in adherence Antibody response to the 45 kDa Candida albicans antigen in an animal model and potential role of the antigen in adherence Účinek protilatek proti 45 kDa proteinovému antigenu z Candidy albicans ve zvířecím modelu a jeho potenciální role v adherenci
skos:prefLabel
Antibody response to the 45 kDa Candida albicans antigen in an animal model and potential role of the antigen in adherence Účinek protilatek proti 45 kDa proteinovému antigenu z Candidy albicans ve zvířecím modelu a jeho potenciální role v adherenci Antibody response to the 45 kDa Candida albicans antigen in an animal model and potential role of the antigen in adherence
skos:notation
RIV/61388963:_____/08:00316278!RIV09-AV0-61388963
n3:aktivita
n16:Z n16:P
n3:aktivity
P(LC531), Z(AV0Z40550506)
n3:cisloPeriodika
12
n3:dodaniDat
n11:2009
n3:domaciTvurceVysledku
n18:2264102
n3:druhVysledku
n17:J
n3:duvernostUdaju
n15:S
n3:entitaPredkladatele
n10:predkladatel
n3:idSjednocenehoVysledku
356401
n3:idVysledku
RIV/61388963:_____/08:00316278
n3:jazykVysledku
n8:eng
n3:klicovaSlova
candida albicans; CR3-RP antigen; adherence
n3:klicoveSlovo
n14:candida%20albicans n14:adherence n14:CR3-RP%20antigen
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[BD1DF8C77699]
n3:nazevZdroje
Journal of Medical Microbiology
n3:obor
n6:CE
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
11
n3:projekt
n7:LC531
n3:rokUplatneniVysledku
n11:2008
n3:svazekPeriodika
57
n3:tvurceVysledku
Jensen, D. B. Kucharíková, S. Chorvát, D. Pichová, Iva Borecká-Melkusová, S. Lell, C. Gašperík, J. Würzner, R. Paulovičová, E. Kolecká, A. Bujdáková, J.
n3:wos
000261660600003
n3:zamer
n12:AV0Z40550506
s:issn
0022-2615
s:numberOfPages
7