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Statements

Subject Item
n2:RIV%2F61388963%3A_____%2F05%3A00022984%21RIV06-GA0-61388963
rdf:type
skos:Concept n17:Vysledek
dcterms:description
Byly syntetizovány 9-mery 5’-d(GTG ATA TGC)-3’ (T je modifikovaná jednotka), které obsahovaly jak hydroxyfosfonátové tak fosfodiesterové 2’-5’ internukleotidové vazby a byla zkoumána jejich hybridizační selektivita vůči DNA and RNA. Synthesis and hybridization selectivity of 9-mers 5’-d(GTG ATA TGC)-3’ (T means modified units) containing both hydroxyphosphonate and phosphodiester 2’-5’ internucleotide linkages toward complementary DNA and RNA counterpart were investigated. Synthesis and hybridization selectivity of 9-mers 5’-d(GTG ATA TGC)-3’ (T means modified units) containing both hydroxyphosphonate and phosphodiester 2’-5’ internucleotide linkages toward complementary DNA and RNA counterpart were investigated.
dcterms:title
2',5'-linked oligo-3'-deoxynucleotide chimeras with chiral alpha-hydroxyphosphonate internucleotide linkage: Improvement of hybridisation selectivity toward RNA? 2',5'-linked oligo-3'-deoxynucleotide chimeras with chiral alpha-hydroxyphosphonate internucleotide linkage: Improvement of hybridisation selectivity toward RNA? Oligo-3'-deoxynukleotidy s chirální alfa-hydroxyfosfonátovou 2',5' internukleotidovou vazbou: zlepšení hybridizační selektivity vůči RNA?
skos:prefLabel
2',5'-linked oligo-3'-deoxynucleotide chimeras with chiral alpha-hydroxyphosphonate internucleotide linkage: Improvement of hybridisation selectivity toward RNA? Oligo-3'-deoxynukleotidy s chirální alfa-hydroxyfosfonátovou 2',5' internukleotidovou vazbou: zlepšení hybridizační selektivity vůči RNA? 2',5'-linked oligo-3'-deoxynucleotide chimeras with chiral alpha-hydroxyphosphonate internucleotide linkage: Improvement of hybridisation selectivity toward RNA?
skos:notation
RIV/61388963:_____/05:00022984!RIV06-GA0-61388963
n6:strany
421;422
n6:aktivita
n14:Z n14:P
n6:aktivity
P(GP203/04/P273), P(IAA4055101), Z(AV0Z40550506)
n6:dodaniDat
n7:2006
n6:domaciTvurceVysledku
n9:4235010 n9:8253536 n9:7035616 n9:6236219 n9:9241299
n6:druhVysledku
n21:D
n6:duvernostUdaju
n16:S
n6:entitaPredkladatele
n18:predkladatel
n6:idSjednocenehoVysledku
552700
n6:idVysledku
RIV/61388963:_____/05:00022984
n6:jazykVysledku
n19:eng
n6:klicovaSlova
oligonucleotides; hydroxyphosphonates; 2'-5' linkage
n6:klicoveSlovo
n12:oligonucleotides n12:hydroxyphosphonates n12:2%27-5%27%20linkage
n6:kontrolniKodProRIV
[438072D3B41D]
n6:mistoKonaniAkce
Špindlerův Mlýn
n6:mistoVydani
Praha
n6:nazevZdroje
Chemistry of Nucleic Acid Components
n6:obor
n15:CC
n6:pocetDomacichTvurcuVysledku
5
n6:pocetTvurcuVysledku
5
n6:projekt
n8:GP203%2F04%2FP273 n8:IAA4055101
n6:rokUplatneniVysledku
n7:2005
n6:tvurceVysledku
Liboska, Radek Rosenberg, Ivan Králíková, Šárka Buděšínský, Miloš Páv, Ondřej
n6:typAkce
n20:WRD
n6:zahajeniAkce
2005-09-03+02:00
n6:zamer
n10:AV0Z40550506
s:numberOfPages
2
n11:hasPublisher
Ústav organické chemie a biochemie AV ČR
n13:isbn
80-86241-25-4