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Statements

Subject Item
n2:RIV%2F61388955%3A_____%2F10%3A00349339%21RIV11-GA0-61388955
rdf:type
skos:Concept n17:Vysledek
dcterms:description
It is shown that the initial biomechanical stability of the applied COC/PE blend in the treated tissue locality, the initial integrity of biomaterials substituting the subchondral bone by polymer implant, the initial bearing capacity and the vertical position of these biomaterials have a mayor influence on the regeneration of new articular cartilage and subchondral bone. These aspects are essential for a prosperous treatment of osteochondral defects. Results reveal that the initial biomechanical stiffness of materials (substituting the subchondral bone) has a fundamental influence on both the quality and the quantity of new articular cartilage and subchondral bone. Research is also aimed at the application of suitable biologically tolerated polymer material, its surface modifications, verifications of the vertical position of implants in relation to the articular cartilage surface and ensuring the initial biomechanical stability of the polymer implant. It is shown that the initial biomechanical stability of the applied COC/PE blend in the treated tissue locality, the initial integrity of biomaterials substituting the subchondral bone by polymer implant, the initial bearing capacity and the vertical position of these biomaterials have a mayor influence on the regeneration of new articular cartilage and subchondral bone. These aspects are essential for a prosperous treatment of osteochondral defects. Results reveal that the initial biomechanical stiffness of materials (substituting the subchondral bone) has a fundamental influence on both the quality and the quantity of new articular cartilage and subchondral bone. Research is also aimed at the application of suitable biologically tolerated polymer material, its surface modifications, verifications of the vertical position of implants in relation to the articular cartilage surface and ensuring the initial biomechanical stability of the polymer implant.
dcterms:title
Cycloolefin-Copolymer/Polyethylene (COC/PE) Blend Assists with the Creation of New Articular Cartilage Cycloolefin-Copolymer/Polyethylene (COC/PE) Blend Assists with the Creation of New Articular Cartilage
skos:prefLabel
Cycloolefin-Copolymer/Polyethylene (COC/PE) Blend Assists with the Creation of New Articular Cartilage Cycloolefin-Copolymer/Polyethylene (COC/PE) Blend Assists with the Creation of New Articular Cartilage
skos:notation
RIV/61388955:_____/10:00349339!RIV11-GA0-61388955
n3:aktivita
n15:P n15:V n15:Z
n3:aktivity
P(GA106/06/0761), V, Z(AV0Z40400503), Z(AV0Z40500505)
n3:cisloPeriodika
-
n3:dodaniDat
n6:2011
n3:domaciTvurceVysledku
n14:7579543
n3:druhVysledku
n16:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n13:predkladatel
n3:idSjednocenehoVysledku
252606
n3:idVysledku
RIV/61388955:_____/10:00349339
n3:jazykVysledku
n11:eng
n3:klicovaSlova
articular cartilage; biomaterials; cycloolefin-copolymer blend
n3:klicoveSlovo
n4:biomaterials n4:cycloolefin-copolymer%20blend n4:articular%20cartilage
n3:kodStatuVydavatele
DE - Spolková republika Německo
n3:kontrolniKodProRIV
[28FF2EF83E35]
n3:nazevZdroje
Macromolecular Symposia
n3:obor
n10:CF
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
8
n3:projekt
n12:GA106%2F06%2F0761
n3:rokUplatneniVysledku
n6:2010
n3:svazekPeriodika
294-I
n3:tvurceVysledku
Lísal, J. Petrtýl, M. Bastl, Zdeněk Polanská, M. Kruliš, Zdeněk Danešová, J. Hulejová, H. Černý, P.
n3:wos
000282840400011
n3:zamer
n9:AV0Z40500505 n9:AV0Z40400503
s:issn
1022-1360
s:numberOfPages
13