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Statements

Subject Item
n2:RIV%2F61388955%3A_____%2F03%3A54030270%21RIV%2F2004%2FAV0%2FA54004%2FN
rdf:type
skos:Concept n18:Vysledek
dcterms:description
Mechanisms of water flow across the peritoneal membrane include diffusion, convection and reabsorption. To understand these processes more clearly we have developed a method to measure transport of water across the peritoneal membrane. An artificial gradient of deuterated water (HDO) between blood and dialysate compartments was created in 5 subjects who took 0.3g per kg of body weight of D2O, which was allowed to equilibrate with total body water. During a test dwell (2L, bicarbonate:lactate buffer, 1.36% glucose to minimise convection), frequent dialysate samples were drawn to determine the abundance of deuterium and other solutes and to calculate their time constants. Dialysate deuterium abundance was measured using flowing afterglow mass spectrometry, FA-MS. Mechanisms of water flow across the peritoneal membrane include diffusion, convection and reabsorption. To understand these processes more clearly we have developed a method to measure transport of water across the peritoneal membrane. An artificial gradient of deuterated water (HDO) between blood and dialysate compartments was created in 5 subjects who took 0.3g per kg of body weight of D2O, which was allowed to equilibrate with total body water. During a test dwell (2L, bicarbonate:lactate buffer, 1.36% glucose to minimise convection), frequent dialysate samples were drawn to determine the abundance of deuterium and other solutes and to calculate their time constants. Dialysate deuterium abundance was measured using flowing afterglow mass spectrometry, FA-MS.
dcterms:title
Measuring Transport of Water Across the Peritoneal Membrane. Measuring Transport of Water Across the Peritoneal Membrane.
skos:prefLabel
Measuring Transport of Water Across the Peritoneal Membrane. Measuring Transport of Water Across the Peritoneal Membrane.
skos:notation
RIV/61388955:_____/03:54030270!RIV/2004/AV0/A54004/N
n3:strany
1911;1915
n3:aktivita
n7:Z n7:P
n3:aktivity
P(GA202/03/0827), Z(AV0Z4040901)
n3:cisloPeriodika
N/A
n3:dodaniDat
n9:2004
n3:domaciTvurceVysledku
n12:9912479
n3:druhVysledku
n13:J
n3:duvernostUdaju
n10:S
n3:entitaPredkladatele
n15:predkladatel
n3:idSjednocenehoVysledku
614641
n3:idVysledku
RIV/61388955:_____/03:54030270
n3:jazykVysledku
n17:eng
n3:klicovaSlova
deuterium; total body water; solute transport
n3:klicoveSlovo
n4:total%20body%20water n4:deuterium n4:solute%20transport
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[BA257C841498]
n3:nazevZdroje
Kidney International
n3:obor
n11:CF
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
5
n3:pocetUcastnikuAkce
0
n3:pocetZahranicnichUcastnikuAkce
0
n3:projekt
n16:GA202%2F03%2F0827
n3:rokUplatneniVysledku
n9:2003
n3:svazekPeriodika
64
n3:tvurceVysledku
Davies, S. J. Asghar, R. B. Španěl, Patrik Smith, D. Diskin, A. M.
n3:zamer
n14:AV0Z4040901
s:issn
0085-2538
s:numberOfPages
5