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Statements

Subject Item
n2:RIV%2F61383082%3A_____%2F11%3A0071%21RIV12-MO0-61383082
rdf:type
skos:Concept n3:Vysledek
dcterms:description
No differences were found in the frequencies of each particular allele of both genes, between HCV patients and a control group (p > 0.05). Furthermore, no association was detected (p > 0.05) between either the HMOX1 or the UGT1A1 promoter variants and the individual histological stages of liver disease in the HCV positive patients. Finally, no differences in the HMOX1 and UGT1A1 genotype prevalence rates were found between pre-cirrhotic and cirrhotic patients (p > 0.05). Based on our data, microsatellite variations in the HMOX1 and UGT1A1 genes are not likely to protect from progression of liver disease in patients with chronic hepatitis C. No differences were found in the frequencies of each particular allele of both genes, between HCV patients and a control group (p > 0.05). Furthermore, no association was detected (p > 0.05) between either the HMOX1 or the UGT1A1 promoter variants and the individual histological stages of liver disease in the HCV positive patients. Finally, no differences in the HMOX1 and UGT1A1 genotype prevalence rates were found between pre-cirrhotic and cirrhotic patients (p > 0.05). Based on our data, microsatellite variations in the HMOX1 and UGT1A1 genes are not likely to protect from progression of liver disease in patients with chronic hepatitis C.
dcterms:title
No association of promoter variations of HMOX1 and UGT1A1 genes with liver injury in chronic hepatitis C No association of promoter variations of HMOX1 and UGT1A1 genes with liver injury in chronic hepatitis C
skos:prefLabel
No association of promoter variations of HMOX1 and UGT1A1 genes with liver injury in chronic hepatitis C No association of promoter variations of HMOX1 and UGT1A1 genes with liver injury in chronic hepatitis C
skos:notation
RIV/61383082:_____/11:0071!RIV12-MO0-61383082
n3:predkladatel
n4:ico%3A61383082
n5:aktivita
n15:P n15:I n15:V
n5:aktivity
I, P(NR9412), V
n5:cisloPeriodika
4
n5:dodaniDat
n12:2012
n5:domaciTvurceVysledku
n17:6699243
n5:druhVysledku
n10:J
n5:duvernostUdaju
n16:S
n5:entitaPredkladatele
n14:predkladatel
n5:idSjednocenehoVysledku
216110
n5:idVysledku
RIV/61383082:_____/11:0071
n5:jazykVysledku
n11:eng
n5:klicovaSlova
Hemoxygenase; biliverdinreduktase
n5:klicoveSlovo
n18:Hemoxygenase n18:biliverdinreduktase
n5:kodStatuVydavatele
MX - Spojené státy mexické
n5:kontrolniKodProRIV
[42A41B375580]
n5:nazevZdroje
Annals of hepatology
n5:obor
n13:FE
n5:pocetDomacichTvurcuVysledku
1
n5:pocetTvurcuVysledku
9
n5:projekt
n6:NR9412
n5:rokUplatneniVysledku
n12:2011
n5:svazekPeriodika
10
n5:tvurceVysledku
Urbánek, Petr Kaspříková, N. Leníček, M. Hrabal, P. Subhanová, I. Bruha, R. Dušek, L. Vítek, L. Muchová, L.
s:issn
1665-2681
s:numberOfPages
7