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Statements

Subject Item
n2:RIV%2F61383082%3A_____%2F11%3A0062%21RIV12-MO0-61383082
rdf:type
skos:Concept n14:Vysledek
dcterms:description
Based on the clinical observation that patients suffering from narcolepsy with cataplexy (NC) have cataplectic attacks when they experience positive emotions, it is therefore hypothesised that the abnormal processing of external emotional input through the limbic system, or motor dysregulation induced by emotions, takes place during these episodes. To date, imaging studies have failed to reveal consistent brain abnormalities in NC patients. METHODS: Considering the discrepancies in reported structural or functional abnormalities of the hypothalamus, amygdala, and nucleus accumbens, we used the MRI volumetry to determine the volumes of the amygdala and nucleus accumbens in a group of eleven patients with NC (5 males and 6 females, mean age 41.7 years ± 17.7). Based on the clinical observation that patients suffering from narcolepsy with cataplexy (NC) have cataplectic attacks when they experience positive emotions, it is therefore hypothesised that the abnormal processing of external emotional input through the limbic system, or motor dysregulation induced by emotions, takes place during these episodes. To date, imaging studies have failed to reveal consistent brain abnormalities in NC patients. METHODS: Considering the discrepancies in reported structural or functional abnormalities of the hypothalamus, amygdala, and nucleus accumbens, we used the MRI volumetry to determine the volumes of the amygdala and nucleus accumbens in a group of eleven patients with NC (5 males and 6 females, mean age 41.7 years ± 17.7).
dcterms:title
Volume of the amygdala is reduced in patients with narcolepsy – a structural MRI study Volume of the amygdala is reduced in patients with narcolepsy – a structural MRI study
skos:prefLabel
Volume of the amygdala is reduced in patients with narcolepsy – a structural MRI study Volume of the amygdala is reduced in patients with narcolepsy – a structural MRI study
skos:notation
RIV/61383082:_____/11:0062!RIV12-MO0-61383082
n14:predkladatel
n17:ico%3A61383082
n3:aktivita
n5:P n5:V
n3:aktivity
P(NR8931), P(NS10331), V
n3:cisloPeriodika
5
n3:dodaniDat
n15:2012
n3:domaciTvurceVysledku
n4:8591644
n3:druhVysledku
n7:J
n3:duvernostUdaju
n11:S
n3:entitaPredkladatele
n10:predkladatel
n3:idSjednocenehoVysledku
239527
n3:idVysledku
RIV/61383082:_____/11:0062
n3:jazykVysledku
n18:eng
n3:klicovaSlova
Narcolepsy; cataplexy; MRI volumetry; amygdala; nucleus accumbens
n3:klicoveSlovo
n9:MRI%20volumetry n9:Narcolepsy n9:cataplexy n9:nucleus%20accumbens n9:amygdala
n3:kodStatuVydavatele
SE - Švédské království
n3:kontrolniKodProRIV
[4AA3092D71E4]
n3:nazevZdroje
NeuroEndocrinology Letters
n3:obor
n16:FH
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
12
n3:projekt
n8:NS10331 n8:NR8931
n3:rokUplatneniVysledku
n15:2011
n3:svazekPeriodika
35
n3:tvurceVysledku
Brabec, J. Hořínek, Daniel
s:issn
0172-780X
s:numberOfPages
5