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Statements

Subject Item
n2:RIV%2F60461373%3A22810%2F13%3A43896627%21RIV14-GA0-22810___
rdf:type
skos:Concept n7:Vysledek
rdfs:seeAlso
http://onlinelibrary.wiley.com/doi/10.1107/S0108270113004708/abstract
dcterms:description
A new substance, cis-amminedibromido(2-methylpyridine-N)platinum(II), cis-[PtBr2(C6H7N)(NH3)], which is a potential platinum-based antineoplastic agent for the treatment of patients with solid tumors, has been synthesized and structurally characterized. There is one molecule in the asymmetric unit and molecules are linked via two symmetry-independent NH...Br hydrogen bonds into zigzag chains running parallel to the c axis. CH...Br hydrogen bonds crosslink these chains to give a layer parallel to (010). NH...Br hydrogen bonds and stacking interactions between pairs of pyridine rings stack the layers along b. A new substance, cis-amminedibromido(2-methylpyridine-N)platinum(II), cis-[PtBr2(C6H7N)(NH3)], which is a potential platinum-based antineoplastic agent for the treatment of patients with solid tumors, has been synthesized and structurally characterized. There is one molecule in the asymmetric unit and molecules are linked via two symmetry-independent NH...Br hydrogen bonds into zigzag chains running parallel to the c axis. CH...Br hydrogen bonds crosslink these chains to give a layer parallel to (010). NH...Br hydrogen bonds and stacking interactions between pairs of pyridine rings stack the layers along b.
dcterms:title
A bromine analogue of picoplatin: a new substance from the group of platinum-based chemotherapeutics A bromine analogue of picoplatin: a new substance from the group of platinum-based chemotherapeutics
skos:prefLabel
A bromine analogue of picoplatin: a new substance from the group of platinum-based chemotherapeutics A bromine analogue of picoplatin: a new substance from the group of platinum-based chemotherapeutics
skos:notation
RIV/60461373:22810/13:43896627!RIV14-GA0-22810___
n7:predkladatel
n8:orjk%3A22810
n3:aktivita
n17:P
n3:aktivity
P(GAP106/12/1276)
n3:cisloPeriodika
4
n3:dodaniDat
n6:2014
n3:domaciTvurceVysledku
n11:2577747 n11:6104339
n3:druhVysledku
n13:J
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
58447
n3:idVysledku
RIV/60461373:22810/13:43896627
n3:jazykVysledku
n18:eng
n3:klicovaSlova
chemotherapeutics; platinum-based; picoplatin; bromine analogue
n3:klicoveSlovo
n4:picoplatin n4:bromine%20analogue n4:platinum-based n4:chemotherapeutics
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[13CE4E4A85BC]
n3:nazevZdroje
Acta Crystallographica Section C: Crystal Structure Communications
n3:obor
n20:CC
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
5
n3:projekt
n19:GAP106%2F12%2F1276
n3:rokUplatneniVysledku
n6:2013
n3:svazekPeriodika
69
n3:tvurceVysledku
Hrdá, Michaela Pažout, Richard Kačer, Petr Maixner, Jaroslav Loužilová, Tereza
n3:wos
000317614900007
s:issn
0108-2701
s:numberOfPages
3
n15:doi
10.1107/S0108270113004708
n21:organizacniJednotka
22810