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Statements

Subject Item
n2:RIV%2F60461373%3A22640%2F01%3A00004693%21RIV%2F2004%2FGA0%2F226404%2FN
rdf:type
n3:Vysledek skos:Concept
dcterms:description
Mason-Pfizer monkey virus encodes an aspartic protease (M-PMV PR), which is essential for the maturation of the virion particles by processing viral protein precursors yielding fully functional structural proteins and enzymes. The overall fold of all known retroviral proteases is quite conservative despite rather large varieties of their amino acid sequences. However, Mason-Pfizer Monkey Virus protease exists in three active forms, which is a feature making this enzyme unique within the this family. In vivo Mason-Pfizer Monkey Virus protease occurs as a 17 kDa (per monomer) molecule. In vitro it undergoes a rapid self-processing at the C-terminus yielding 13 kDa and finally 12 kDa forms [1]. We will present backbone resonance assignment and secondary structure identification of shortest 12 kDa form of protease from Mason-Pfizer Monkey Virus [2]. Mason-Pfizer monkey virus encodes an aspartic protease (M-PMV PR), which is essential for the maturation of the virion particles by processing viral protein precursors yielding fully functional structural proteins and enzymes. The overall fold of all known retroviral proteases is quite conservative despite rather large varieties of their amino acid sequences. However, Mason-Pfizer Monkey Virus protease exists in three active forms, which is a feature making this enzyme unique within the this family. In vivo Mason-Pfizer Monkey Virus protease occurs as a 17 kDa (per monomer) molecule. In vitro it undergoes a rapid self-processing at the C-terminus yielding 13 kDa and finally 12 kDa forms [1]. We will present backbone resonance assignment and secondary structure identification of shortest 12 kDa form of protease from Mason-Pfizer Monkey Virus [2].
dcterms:title
Backbone resonance assignment of protease from Mason-Pfizer monkey virus Backbone resonance assignment of protease from Mason-Pfizer monkey virus
skos:prefLabel
Backbone resonance assignment of protease from Mason-Pfizer monkey virus Backbone resonance assignment of protease from Mason-Pfizer monkey virus
skos:notation
RIV/60461373:22640/01:00004693!RIV/2004/GA0/226404/N
n4:strany
291-292
n4:aktivita
n14:P
n4:aktivity
P(GA203/00/1241)
n4:cisloPeriodika
3
n4:dodaniDat
n7:2004
n4:domaciTvurceVysledku
n13:7847440 n13:4866754
n4:druhVysledku
n15:J
n4:duvernostUdaju
n18:S
n4:entitaPredkladatele
n16:predkladatel
n4:idSjednocenehoVysledku
674124
n4:idVysledku
RIV/60461373:22640/01:00004693
n4:jazykVysledku
n12:eng
n4:klicovaSlova
NMR spectroscopy, protease, Mason-Pfizer virus
n4:klicoveSlovo
n5:protease n5:Mason-Pfizer%20virus n5:NMR%20spectroscopy
n4:kodStatuVydavatele
NL - Nizozemsko
n4:kontrolniKodProRIV
[0F6081461997]
n4:nazevZdroje
Journal of Biomolecular NMR
n4:obor
n9:CE
n4:pocetDomacichTvurcuVysledku
2
n4:pocetTvurcuVysledku
5
n4:pocetUcastnikuAkce
0
n4:pocetZahranicnichUcastnikuAkce
0
n4:projekt
n17:GA203%2F00%2F1241
n4:rokUplatneniVysledku
n7:2001
n4:svazekPeriodika
20
n4:tvurceVysledku
Hrabal, Richard Bauerová, Helena Pichová, Iva Veverka, Václav Zábranský, Aleš
s:issn
0925-2738
s:numberOfPages
2
n8:organizacniJednotka
22640