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Statements

Subject Item
n2:RIV%2F60461373%3A22340%2F14%3A43897688%21RIV15-MSM-22340___
rdf:type
n3:Vysledek skos:Concept
dcterms:description
The goal was to prepare composite lipide/Fe3O4/SiO2 nanoparticles from hollow porous silica shell nanoparticles (100-300 nm) prepared by soft template emulsion method, magnetic iron oxide nanoparticles (5-20 nm) prepared by co-precipitation method and lipide nanoparticles (20-40 nm) prepared by high pressure homogenization.. First composite Fe3O4/SiO2 nanoparticles were prepared by coating silica with monolayer of iron oxide. The composite particles was then loaded with active substance and coated with layer of lipide nanoparticles to form oclusive lipide barrier which block diffusion in and out of the particles, thus preserving the active substance inside. The particles were cahracterised using transmission electron microscopy, dynamic light scattering and electrophoretic light scattering. The release mechanism is triggered by alternating radiofrequency field which heats up the magnetic iron oxide particles and melts the lipidic barrier which opens pores and the active substance diffuses into the environment. Release kinetics of the active substance were measured using UV-VIS spectrophotometer. The goal was to prepare composite lipide/Fe3O4/SiO2 nanoparticles from hollow porous silica shell nanoparticles (100-300 nm) prepared by soft template emulsion method, magnetic iron oxide nanoparticles (5-20 nm) prepared by co-precipitation method and lipide nanoparticles (20-40 nm) prepared by high pressure homogenization.. First composite Fe3O4/SiO2 nanoparticles were prepared by coating silica with monolayer of iron oxide. The composite particles was then loaded with active substance and coated with layer of lipide nanoparticles to form oclusive lipide barrier which block diffusion in and out of the particles, thus preserving the active substance inside. The particles were cahracterised using transmission electron microscopy, dynamic light scattering and electrophoretic light scattering. The release mechanism is triggered by alternating radiofrequency field which heats up the magnetic iron oxide particles and melts the lipidic barrier which opens pores and the active substance diffuses into the environment. Release kinetics of the active substance were measured using UV-VIS spectrophotometer.
dcterms:title
Synthesis and characterization of composite hollow porous lipide/fe3o4/sio2 nanoparticles for controlled release of active substances Synthesis and characterization of composite hollow porous lipide/fe3o4/sio2 nanoparticles for controlled release of active substances
skos:prefLabel
Synthesis and characterization of composite hollow porous lipide/fe3o4/sio2 nanoparticles for controlled release of active substances Synthesis and characterization of composite hollow porous lipide/fe3o4/sio2 nanoparticles for controlled release of active substances
skos:notation
RIV/60461373:22340/14:43897688!RIV15-MSM-22340___
n6:aktivita
n20:S
n6:aktivity
S
n6:dodaniDat
n15:2015
n6:domaciTvurceVysledku
n10:2093928 n10:6584470 n10:4022378 n10:4595556
n6:druhVysledku
n17:D
n6:duvernostUdaju
n7:S
n6:entitaPredkladatele
n13:predkladatel
n6:idSjednocenehoVysledku
48967
n6:idVysledku
RIV/60461373:22340/14:43897688
n6:jazykVysledku
n18:eng
n6:klicovaSlova
controlled release; lipide/fe3o4/sio2 nanoparticles; porous; hollow; composite
n6:klicoveSlovo
n9:porous n9:hollow n9:lipide%2Ffe3o4%2Fsio2%20nanoparticles n9:composite n9:controlled%20release
n6:kontrolniKodProRIV
[4128A895DFD4]
n6:mistoKonaniAkce
Tatranské Matliare
n6:mistoVydani
Bratislava
n6:nazevZdroje
Proceedings of the 41st International Conference of Slovak Society of Chemical Engineering
n6:obor
n12:CI
n6:pocetDomacichTvurcuVysledku
4
n6:pocetTvurcuVysledku
4
n6:rokUplatneniVysledku
n15:2014
n6:tvurceVysledku
Vidlářová, Lucie Štěpánek, František Šoltys, Marek Kovačík, Pavel
n6:typAkce
n19:EUR
n6:zahajeniAkce
2014-05-26+02:00
s:numberOfPages
10
n14:hasPublisher
Slovak Society of Chemical Engineering
n16:isbn
978-80-89475-13-1
n11:organizacniJednotka
22340