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Statements

Subject Item
n2:RIV%2F60461373%3A22340%2F12%3A43894822%21RIV13-GA0-22340___
rdf:type
n8:Vysledek skos:Concept
dcterms:description
The nowadays commonly used term asthma comes from Greek language and means %22panting%22. Currently, asthma is defined as a chronic inflammatory disorder of the airways where many cells and cellular elements play significant roles. In susceptible individuals, this inflammation causes recurrent episodes of wheezing, breathlessness and chest tightness accompanied by coughing, occurring very often during the night or early morning. These episodes are widely associated with a variable airflow obstruction that is either spontaneously reversible, or controllable by a suitable treatment. Asthma can be controlled by recognizing its alarming signs and by avoiding stimuli triggering the attack. During an asthma episode, the airways become extremely narrow due to a muscle constriction, swelling of the inner lining and a mucus production. These repetitive episodes can cause a very limited airflow and may lead to unexpected fatalities. Factors, playing role in bronchial asthma can be divided into three groups. Among the first, internal factors are such as genetic predisposition and the state of immune system. The second factors are classified as external triggers and include for example allergens like pollen, mold spores, dust mites or animal dander. However, indoor and outdoor pollutants and irritants such as smoke, perfumes, cleaning agents, etc., can also belong to this group. The third group consists of physical factors, especially exercise and cold air, and physiological factors like stress, gastroesophageal reflux disease (GERD) or viral and bacterial upper respiratory infection. Severity of asthma is traditionally classified as mild, moderate and severe depending on its symptoms, rescue inhaler use and function parameters of lungs. While on controller therapy, each of these groups is further classified as well controlled, not well controlled or poorly controlled, based on the presence and frequency of symptoms, and lung function. The nowadays commonly used term asthma comes from Greek language and means %22panting%22. Currently, asthma is defined as a chronic inflammatory disorder of the airways where many cells and cellular elements play significant roles. In susceptible individuals, this inflammation causes recurrent episodes of wheezing, breathlessness and chest tightness accompanied by coughing, occurring very often during the night or early morning. These episodes are widely associated with a variable airflow obstruction that is either spontaneously reversible, or controllable by a suitable treatment. Asthma can be controlled by recognizing its alarming signs and by avoiding stimuli triggering the attack. During an asthma episode, the airways become extremely narrow due to a muscle constriction, swelling of the inner lining and a mucus production. These repetitive episodes can cause a very limited airflow and may lead to unexpected fatalities. Factors, playing role in bronchial asthma can be divided into three groups. Among the first, internal factors are such as genetic predisposition and the state of immune system. The second factors are classified as external triggers and include for example allergens like pollen, mold spores, dust mites or animal dander. However, indoor and outdoor pollutants and irritants such as smoke, perfumes, cleaning agents, etc., can also belong to this group. The third group consists of physical factors, especially exercise and cold air, and physiological factors like stress, gastroesophageal reflux disease (GERD) or viral and bacterial upper respiratory infection. Severity of asthma is traditionally classified as mild, moderate and severe depending on its symptoms, rescue inhaler use and function parameters of lungs. While on controller therapy, each of these groups is further classified as well controlled, not well controlled or poorly controlled, based on the presence and frequency of symptoms, and lung function.
dcterms:title
Determination of Biomarkers in Exhaled Breath Condensate: A Perspective Way in Bronchial Asthma Diagnostics Determination of Biomarkers in Exhaled Breath Condensate: A Perspective Way in Bronchial Asthma Diagnostics
skos:prefLabel
Determination of Biomarkers in Exhaled Breath Condensate: A Perspective Way in Bronchial Asthma Diagnostics Determination of Biomarkers in Exhaled Breath Condensate: A Perspective Way in Bronchial Asthma Diagnostics
skos:notation
RIV/60461373:22340/12:43894822!RIV13-GA0-22340___
n8:predkladatel
n17:orjk%3A22340
n3:aktivita
n7:Z n7:P
n3:aktivity
P(GD203/08/H032), P(NS10298), Z(MSM6046137301)
n3:dodaniDat
n10:2013
n3:domaciTvurceVysledku
n20:5219965
n3:druhVysledku
n13:C
n3:duvernostUdaju
n6:S
n3:entitaPredkladatele
n21:predkladatel
n3:idSjednocenehoVysledku
130558
n3:idVysledku
RIV/60461373:22340/12:43894822
n3:jazykVysledku
n16:eng
n3:klicovaSlova
Bronchial asthma, leukotrienes, exhaled breath condensate, HPLC-MS/MS.
n3:klicoveSlovo
n11:exhaled%20breath%20condensate n11:Bronchial%20asthma n11:leukotrienes n11:HPLC-MS%2FMS.
n3:kontrolniKodProRIV
[2D09C732B399]
n3:mistoVydani
Rijeka
n3:nazevZdroje
Bronchial Asthma - Emerging Therapeutic Strategies
n3:obor
n12:CB
n3:pocetDomacichTvurcuVysledku
1
n3:pocetStranKnihy
260
n3:pocetTvurcuVysledku
5
n3:projekt
n14:NS10298 n14:GD203%2F08%2FH032
n3:rokUplatneniVysledku
n10:2012
n3:tvurceVysledku
Kuzma, Marek Kačer, Petr Novotný, Petr Syslová, Kamila Pelclová, Daniela
n3:zamer
n19:MSM6046137301
s:numberOfPages
37
n15:hasPublisher
InTech
n18:isbn
978-953-51-0140-6
n22:organizacniJednotka
22340