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Statements

Subject Item
n2:RIV%2F60461373%3A22340%2F12%3A43893175%21RIV13-MSM-22340___
rdf:type
skos:Concept n11:Vysledek
dcterms:description
To evaluate the frequencies of symptoms and signs in patients with posterior circulation ischemia in a large case series of prospectively collected patients. All patients were examined by senior stroke neurologists. All patients had either computed tomography or magnetic resonance imaging of the brain as well as vascular imaging of the head and neck. The study included 256 men (63%) and 151 women (37%). These outcome measures were planned before data collection began. Correlations between symptoms and signs with separate vascular territories of the posterior circulation were then analyzed. The most frequent posterior circulation symptoms were dizziness (47%), unilateral limb weakness (41%), dysarthria (31%), headache (28%), and nausea or vomiting (27%). The most frequent signs were unilateral limb weakness (38%), gait ataxia (31%), unilateral limb ataxia (30%), dysarthria (28%), and nystagmus (24%). Logistic regression analysis reveals that the clinical features dysphagia (P = .004; 95% CI, 1.8-24.4), nausea or vomiting (P = .002; 95% CI, 1.6-8.2), dizziness (P = .047; 95% CI, 1.0-5.4), and Horner syndrome (P = .001; 95% CI, 2.4-26.6) were positively correlated with the proximal vascular territory. Unilateral limb weakness (P = .001; 95% CI, 1.7-8.7) and cranial nerve VII deficits (P = .02; 95% CI, 1.1-5.3) were positively correlated with the middle territory. Limb sensory deficit (P = .001; 95% CI, 1.8-7.8), lethargy (P = .001; 95% CI, 2.3-12.4), and visual field loss (P = .001; 95% CI, 5.3-23.9) were positively correlated with the distal territory. We report the most frequent symptoms and signs in the largest published registry, the New England Medical Center Posterior Circulation Registry, of patients with posterior circulation ischemia who had complete neurological examinations and extensive cerebrovascular imaging. Knowledge of the vascular territory involved aids in the diagnosis of the causative vascular lesion and stroke mechanism. To evaluate the frequencies of symptoms and signs in patients with posterior circulation ischemia in a large case series of prospectively collected patients. All patients were examined by senior stroke neurologists. All patients had either computed tomography or magnetic resonance imaging of the brain as well as vascular imaging of the head and neck. The study included 256 men (63%) and 151 women (37%). These outcome measures were planned before data collection began. Correlations between symptoms and signs with separate vascular territories of the posterior circulation were then analyzed. The most frequent posterior circulation symptoms were dizziness (47%), unilateral limb weakness (41%), dysarthria (31%), headache (28%), and nausea or vomiting (27%). The most frequent signs were unilateral limb weakness (38%), gait ataxia (31%), unilateral limb ataxia (30%), dysarthria (28%), and nystagmus (24%). Logistic regression analysis reveals that the clinical features dysphagia (P = .004; 95% CI, 1.8-24.4), nausea or vomiting (P = .002; 95% CI, 1.6-8.2), dizziness (P = .047; 95% CI, 1.0-5.4), and Horner syndrome (P = .001; 95% CI, 2.4-26.6) were positively correlated with the proximal vascular territory. Unilateral limb weakness (P = .001; 95% CI, 1.7-8.7) and cranial nerve VII deficits (P = .02; 95% CI, 1.1-5.3) were positively correlated with the middle territory. Limb sensory deficit (P = .001; 95% CI, 1.8-7.8), lethargy (P = .001; 95% CI, 2.3-12.4), and visual field loss (P = .001; 95% CI, 5.3-23.9) were positively correlated with the distal territory. We report the most frequent symptoms and signs in the largest published registry, the New England Medical Center Posterior Circulation Registry, of patients with posterior circulation ischemia who had complete neurological examinations and extensive cerebrovascular imaging. Knowledge of the vascular territory involved aids in the diagnosis of the causative vascular lesion and stroke mechanism.
dcterms:title
Symptoms and Signs of Posterior Circulation Ischemia in the New England Medical Center Posterior Circulation Registry Symptoms and Signs of Posterior Circulation Ischemia in the New England Medical Center Posterior Circulation Registry
skos:prefLabel
Symptoms and Signs of Posterior Circulation Ischemia in the New England Medical Center Posterior Circulation Registry Symptoms and Signs of Posterior Circulation Ischemia in the New England Medical Center Posterior Circulation Registry
skos:notation
RIV/60461373:22340/12:43893175!RIV13-MSM-22340___
n11:predkladatel
n15:orjk%3A22340
n3:aktivita
n4:Z
n3:aktivity
Z(MSM6046137306)
n3:cisloPeriodika
3
n3:dodaniDat
n8:2013
n3:domaciTvurceVysledku
n20:1501208
n3:druhVysledku
n7:J
n3:duvernostUdaju
n17:S
n3:entitaPredkladatele
n12:predkladatel
n3:idSjednocenehoVysledku
172825
n3:idVysledku
RIV/60461373:22340/12:43893175
n3:jazykVysledku
n9:eng
n3:klicovaSlova
frequencies of symptoms and signs; correlations between symptoms and signs; posterior circulation ischemia
n3:klicoveSlovo
n10:correlations%20between%20symptoms%20and%20signs n10:frequencies%20of%20symptoms%20and%20signs n10:posterior%20circulation%20ischemia
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[747533C65590]
n3:nazevZdroje
Archives of Neurology
n3:obor
n18:FH
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
5
n3:rokUplatneniVysledku
n8:2012
n3:svazekPeriodika
69
n3:tvurceVysledku
Korbel, Evžen Vyšata, Oldřich Caplan, Louis R. Pazdera, Ladislav Searls, D. Eric
n3:wos
000301377300007
n3:zamer
n13:MSM6046137306
s:issn
0003-9942
s:numberOfPages
6
n19:doi
10.1001/archneurol.2011.2083
n14:organizacniJednotka
22340