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Statements

Subject Item
n2:RIV%2F60461373%3A22330%2F14%3A43899302%21RIV15-MSM-22330___
rdf:type
n8:Vysledek skos:Concept
dcterms:description
There is always a need to precisely distribute and control the flows in preparative chromatography, because it is the most important part of control in such kind of the process. In most cases the control is being made for one station as a black box with several inputs and outputs. We have made a small module, which can be connected up to the eight-columned station and corresponding number of pumps. It has its own controlling system consisting of controllers based on Siemens Simatic. It allows controlling any continuous process like SMB and VariCol. It consists of system of electromagnetic valves connected together with silicon tubes allowing distribution of flow in several directions. The functionality of distributor and primary control were tested with existing chromatographic unit KCHS-SMB-8-N containing sorbent Lewatit MDS 1368. The initial tests were performed with solutions of saccharides or carbohydrate and salts. The system for higher level control based on optimization and fuzzy logic is now being tested for the SMB mode. In a future, the VariCol system will be also tested using the food technology by-products like molasses and whey with aim to purify saccharides and proteins. There is always a need to precisely distribute and control the flows in preparative chromatography, because it is the most important part of control in such kind of the process. In most cases the control is being made for one station as a black box with several inputs and outputs. We have made a small module, which can be connected up to the eight-columned station and corresponding number of pumps. It has its own controlling system consisting of controllers based on Siemens Simatic. It allows controlling any continuous process like SMB and VariCol. It consists of system of electromagnetic valves connected together with silicon tubes allowing distribution of flow in several directions. The functionality of distributor and primary control were tested with existing chromatographic unit KCHS-SMB-8-N containing sorbent Lewatit MDS 1368. The initial tests were performed with solutions of saccharides or carbohydrate and salts. The system for higher level control based on optimization and fuzzy logic is now being tested for the SMB mode. In a future, the VariCol system will be also tested using the food technology by-products like molasses and whey with aim to purify saccharides and proteins.
dcterms:title
The flow control in continuous chromatography The flow control in continuous chromatography
skos:prefLabel
The flow control in continuous chromatography The flow control in continuous chromatography
skos:notation
RIV/60461373:22330/14:43899302!RIV15-MSM-22330___
n4:aktivita
n11:I
n4:aktivity
I
n4:dodaniDat
n6:2015
n4:domaciTvurceVysledku
Hassan, Nazih n14:1780328 n14:1290916 n14:7774710 n14:3496910
n4:druhVysledku
n9:D
n4:duvernostUdaju
n19:S
n4:entitaPredkladatele
n17:predkladatel
n4:idSjednocenehoVysledku
17050
n4:idVysledku
RIV/60461373:22330/14:43899302
n4:jazykVysledku
n5:eng
n4:klicovaSlova
SMB; flow; continuous chromatography
n4:klicoveSlovo
n13:flow n13:SMB n13:continuous%20chromatography
n4:kontrolniKodProRIV
[F1438F183F7D]
n4:mistoKonaniAkce
Praha
n4:mistoVydani
Praha
n4:nazevZdroje
Proceedings of the 21st International Congress of Chemical and Process Engineering CHISA 2014
n4:obor
n20:GM
n4:pocetDomacichTvurcuVysledku
5
n4:pocetTvurcuVysledku
6
n4:rokUplatneniVysledku
n6:2014
n4:tvurceVysledku
Vejs, L. Pour, Vladimír Hassan, Nazih Henke, Svatopluk Bubník, Zdeněk Hinková, Andrea
n4:typAkce
n18:EUR
n4:zahajeniAkce
2014-08-23+02:00
s:numberOfPages
1
n7:hasPublisher
Česká společnost chemického inženýrství
n15:isbn
978-80-02-02555-9
n12:organizacniJednotka
22330