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Statements

Subject Item
n2:RIV%2F60461373%3A22330%2F09%3A00022116%21RIV10-MSM-22330___
rdf:type
skos:Concept n19:Vysledek
dcterms:description
RNA interference (RNAi) is a natural mechanism that inhibits gene expression at the stage of translation or by blocking the transcription of specific genes. RNAi targets include RNA from viruses and transposons which could contribute to innate immune response. RNAi plays a key role in regulating genom development and its maintenance. Small interfering RNA (siRNA) and micro RNA (miRNA) are a key to the RNAi process. Their nucleotide sequences are complementary to the target mRNA strand. The selective effect of RNAi on gene expression makes it a valuable research tool, both in cell culture and in living organisms, because synthetic dsRNA introduced into cells can induce suppression of specific genes of interest. RNAi may also be used for large-scale screenings that systematically silence expression of genes in the cell, which can help identify the components necessary for a particular cell process. To develop an effective gene-silencing procedure, several approaches to the long-term introduction of RNA RNA interference (RNAi) is a natural mechanism that inhibits gene expression at the stage of translation or by blocking the transcription of specific genes. RNAi targets include RNA from viruses and transposons which could contribute to innate immune response. RNAi plays a key role in regulating genom development and its maintenance. Small interfering RNA (siRNA) and micro RNA (miRNA) are a key to the RNAi process. Their nucleotide sequences are complementary to the target mRNA strand. The selective effect of RNAi on gene expression makes it a valuable research tool, both in cell culture and in living organisms, because synthetic dsRNA introduced into cells can induce suppression of specific genes of interest. RNAi may also be used for large-scale screenings that systematically silence expression of genes in the cell, which can help identify the components necessary for a particular cell process. To develop an effective gene-silencing procedure, several approaches to the long-term introduction of RNA RNA interference (RNAi) is a natural mechanism that inhibits gene expression at the stage of translation or by blocking the transcription of specific genes. RNAi targets include RNA from viruses and transposons which could contribute to innate immune response. RNAi plays a key role in regulating genom development and its maintenance. Small interfering RNA (siRNA) and micro RNA (miRNA) are a key to the RNAi process. Their nucleotide sequences are complementary to the target mRNA strand. The selective effect of RNAi on gene expression makes it a valuable research tool, both in cell culture and in living organisms, because synthetic dsRNA introduced into cells can induce suppression of specific genes of interest. RNAi may also be used for large-scale screenings that systematically silence expression of genes in the cell, which can help identify the components necessary for a particular cell process. To develop an effective gene-silencing procedure, several approaches to the long-term introduction of RNA
dcterms:title
RNA INTERFERENCE A PRAKTICKÉ ASPEKTY JEJÍHO VYUžITÍ RNA Interference and Practical Aspects of Its Application RNA INTERFERENCE A PRAKTICKÉ ASPEKTY JEJÍHO VYUžITÍ
skos:prefLabel
RNA INTERFERENCE A PRAKTICKÉ ASPEKTY JEJÍHO VYUžITÍ RNA Interference and Practical Aspects of Its Application RNA INTERFERENCE A PRAKTICKÉ ASPEKTY JEJÍHO VYUžITÍ
skos:notation
RIV/60461373:22330/09:00022116!RIV10-MSM-22330___
n3:aktivita
n4:P n4:Z
n3:aktivity
P(IAA500110805), Z(MSM6046137305)
n3:cisloPeriodika
4
n3:dodaniDat
n10:2010
n3:domaciTvurceVysledku
n14:2472643 n14:3931390 n14:8225044
n3:druhVysledku
n6:J
n3:duvernostUdaju
n8:S
n3:entitaPredkladatele
n15:predkladatel
n3:idSjednocenehoVysledku
339538
n3:idVysledku
RIV/60461373:22330/09:00022116
n3:jazykVysledku
n12:cze
n3:klicovaSlova
RNA interference; siRNA; miRNA; transfection; cell cultures; biotechnology
n3:klicoveSlovo
n9:miRNA n9:transfection n9:siRNA n9:RNA%20interference n9:biotechnology n9:cell%20cultures
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[D1768BCB65B2]
n3:nazevZdroje
Chemické listy
n3:obor
n17:EB
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
4
n3:projekt
n16:IAA500110805
n3:rokUplatneniVysledku
n10:2009
n3:svazekPeriodika
103
n3:tvurceVysledku
Zídková, Jarmila Škop, Vojtěch Kontrová, Kateřina Sajdok, Jiří
n3:wos
000265518100008
n3:zamer
n7:MSM6046137305
s:issn
0009-2770
s:numberOfPages
7
n18:organizacniJednotka
22330