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Statements

Subject Item
n2:RIV%2F60461373%3A22310%2F14%3A43897512%21RIV15-TA0-22310___
rdf:type
n11:Vysledek skos:Concept
dcterms:description
Hydroxyapatite materials prepared by two methods: synthetic (HA-S) and bovine (HA-B) granules were exposed to a long-term in vitro test under dynamic conditions. Testing cells, filled up to one fourth (?V) of their volume with the tested material, were exposed to continuous flow of simulated body fluid (SBF) for 56 days. The objective of the experiment was to determine whether reactivity of the biomaterials (hydroxyapatites), prepared by different methods but identical in terms of their chemical and phase composition, in SBF were comparable. Analyses of the solutions proved that both materials were highly reactive from the very beginning of interaction with SBF (significant decrease of Ca2+ and (PO4)3- concentrations in the leachate). SEM/EDS images have shown that the surface of bovine HA-B was covered with a new hydroxyapatite (HAp) phase in the first two weeks of the test while synthetic HA-S was covered after two weeks of the immersion in SBF. At the end of the test, day 56, both materials were completely covered with well developed porous HAp phase in form of nano-plates. A calculation of the rate of HAp formation from the concentration of (PO4)3- ions in SBF leachates confirmed that all removed ions were consumed for the formation of the HAp phase throughout the entire testing time for bovine HA-B and only during the second half of the testing time for synthetic HA-S. Hydroxyapatite materials prepared by two methods: synthetic (HA-S) and bovine (HA-B) granules were exposed to a long-term in vitro test under dynamic conditions. Testing cells, filled up to one fourth (?V) of their volume with the tested material, were exposed to continuous flow of simulated body fluid (SBF) for 56 days. The objective of the experiment was to determine whether reactivity of the biomaterials (hydroxyapatites), prepared by different methods but identical in terms of their chemical and phase composition, in SBF were comparable. Analyses of the solutions proved that both materials were highly reactive from the very beginning of interaction with SBF (significant decrease of Ca2+ and (PO4)3- concentrations in the leachate). SEM/EDS images have shown that the surface of bovine HA-B was covered with a new hydroxyapatite (HAp) phase in the first two weeks of the test while synthetic HA-S was covered after two weeks of the immersion in SBF. At the end of the test, day 56, both materials were completely covered with well developed porous HAp phase in form of nano-plates. A calculation of the rate of HAp formation from the concentration of (PO4)3- ions in SBF leachates confirmed that all removed ions were consumed for the formation of the HAp phase throughout the entire testing time for bovine HA-B and only during the second half of the testing time for synthetic HA-S.
dcterms:title
COMPARISON OF REACTIVITY OF SYNTHETIC AND BOVINE HYDROXYAPATITE IN VITRO UNDER DYNAMIC CONDITIONS COMPARISON OF REACTIVITY OF SYNTHETIC AND BOVINE HYDROXYAPATITE IN VITRO UNDER DYNAMIC CONDITIONS
skos:prefLabel
COMPARISON OF REACTIVITY OF SYNTHETIC AND BOVINE HYDROXYAPATITE IN VITRO UNDER DYNAMIC CONDITIONS COMPARISON OF REACTIVITY OF SYNTHETIC AND BOVINE HYDROXYAPATITE IN VITRO UNDER DYNAMIC CONDITIONS
skos:notation
RIV/60461373:22310/14:43897512!RIV15-TA0-22310___
n3:aktivita
n15:P
n3:aktivity
P(TE01020390)
n3:cisloPeriodika
1
n3:dodaniDat
n13:2015
n3:domaciTvurceVysledku
n5:5597951 n5:7488238 n5:6096255 n5:7361114 n5:3875180 n5:1602314
n3:druhVysledku
n10:J
n3:duvernostUdaju
n16:S
n3:entitaPredkladatele
n18:predkladatel
n3:idSjednocenehoVysledku
8165
n3:idVysledku
RIV/60461373:22310/14:43897512
n3:jazykVysledku
n8:eng
n3:klicovaSlova
SBF; in vitro test; Hydroxyapatite
n3:klicoveSlovo
n14:Hydroxyapatite n14:in%20vitro%20test n14:SBF
n3:kodStatuVydavatele
CZ - Česká republika
n3:kontrolniKodProRIV
[D6D561E7FCE9]
n3:nazevZdroje
Ceramics-Silikáty
n3:obor
n4:JH
n3:pocetDomacichTvurcuVysledku
6
n3:pocetTvurcuVysledku
6
n3:projekt
n17:TE01020390
n3:rokUplatneniVysledku
n13:2014
n3:svazekPeriodika
58
n3:tvurceVysledku
Helebrant, Aleš Kuncová, Lenka Rohanová, Dana Horkavcová, Diana Zlámalová Cílová, Zuzana Zítková, Klára
s:issn
0862-5468
s:numberOfPages
9
n12:organizacniJednotka
22310