This HTML5 document contains 45 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
n19http://localhost/temp/predkladatel/
n10http://linked.opendata.cz/resource/domain/vavai/riv/tvurce/
n12http://linked.opendata.cz/resource/domain/vavai/subjekt/
n11http://linked.opendata.cz/ontology/domain/vavai/
n5http://linked.opendata.cz/resource/domain/vavai/zamer/
shttp://schema.org/
skoshttp://www.w3.org/2004/02/skos/core#
n20http://linked.opendata.cz/resource/domain/vavai/vysledek/RIV%2F60461373%3A22310%2F13%3A43895356%21RIV14-MSM-22310___/
n3http://linked.opendata.cz/ontology/domain/vavai/riv/
n4http://bibframe.org/vocab/
n2http://linked.opendata.cz/resource/domain/vavai/vysledek/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
n13http://linked.opendata.cz/ontology/domain/vavai/riv/klicoveSlovo/
n17http://linked.opendata.cz/ontology/domain/vavai/riv/duvernostUdaju/
xsdhhttp://www.w3.org/2001/XMLSchema#
n14http://linked.opendata.cz/ontology/domain/vavai/riv/aktivita/
n6http://linked.opendata.cz/ontology/domain/vavai/riv/jazykVysledku/
n16http://linked.opendata.cz/ontology/domain/vavai/riv/obor/
n9http://linked.opendata.cz/ontology/domain/vavai/riv/druhVysledku/
n18http://reference.data.gov.uk/id/gregorian-year/

Statements

Subject Item
n2:RIV%2F60461373%3A22310%2F13%3A43895356%21RIV14-MSM-22310___
rdf:type
skos:Concept n11:Vysledek
dcterms:description
Rapid and correct production of generic solid dosage forms requires a large amount of analytical data and conclusions. Modern analytical techniques have a good resolution and accuray and allow obtaining a lot of information about the original products. Scanning electron microscopy (SEM) is used for observation infrared (FTIR) spectroscopy mapping allows determining the distribution and characterization of individual components in a solid dosage form. However, the samples prepared by common way, using scalpel or tablet splitter, are not good enough. It was the reason for development of a new and better method of sample preparation, which uses microtome. Well-prepared samples analyzed by SEM and FTIR mapping allow to determine a solid dosage form formulation, excipient content and distribution of excipient and active pharmaceutical ingredient. Rapid and correct production of generic solid dosage forms requires a large amount of analytical data and conclusions. Modern analytical techniques have a good resolution and accuray and allow obtaining a lot of information about the original products. Scanning electron microscopy (SEM) is used for observation infrared (FTIR) spectroscopy mapping allows determining the distribution and characterization of individual components in a solid dosage form. However, the samples prepared by common way, using scalpel or tablet splitter, are not good enough. It was the reason for development of a new and better method of sample preparation, which uses microtome. Well-prepared samples analyzed by SEM and FTIR mapping allow to determine a solid dosage form formulation, excipient content and distribution of excipient and active pharmaceutical ingredient.
dcterms:title
A new way of solid dosage form samples preparation for SEM and FTIR using microtome A new way of solid dosage form samples preparation for SEM and FTIR using microtome
skos:prefLabel
A new way of solid dosage form samples preparation for SEM and FTIR using microtome A new way of solid dosage form samples preparation for SEM and FTIR using microtome
skos:notation
RIV/60461373:22310/13:43895356!RIV14-MSM-22310___
n11:predkladatel
n12:orjk%3A22310
n3:aktivita
n14:Z
n3:aktivity
Z(MSM6046137302)
n3:cisloPeriodika
4
n3:dodaniDat
n18:2014
n3:domaciTvurceVysledku
n10:4264533 n10:4503392
n3:druhVysledku
n9:J
n3:duvernostUdaju
n17:S
n3:entitaPredkladatele
n20:predkladatel
n3:idSjednocenehoVysledku
58862
n3:idVysledku
RIV/60461373:22310/13:43895356
n3:jazykVysledku
n6:eng
n3:klicovaSlova
surface; solid dosage form; scanning electron microscopy; microtome; FTIR mapping; Cut
n3:klicoveSlovo
n13:Cut n13:solid%20dosage%20form n13:FTIR%20mapping n13:scanning%20electron%20microscopy n13:surface n13:microtome
n3:kodStatuVydavatele
GB - Spojené království Velké Británie a Severního Irska
n3:kontrolniKodProRIV
[A78DDBD52B66]
n3:nazevZdroje
Pharmaceutical Development and Technology
n3:obor
n16:CI
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
3
n3:rokUplatneniVysledku
n18:2013
n3:svazekPeriodika
19
n3:tvurceVysledku
Grünwaldová, Veronika Kratochvíl, Bohumil Šimek, Michal
n3:zamer
n5:MSM6046137302
s:issn
1083-7450
s:numberOfPages
6
n4:doi
10.3109/10837450.2013.788515
n19:organizacniJednotka
22310