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Statements

Subject Item
n2:RIV%2F60460709%3A41210%2F11%3A50330%21RIV12-MSM-41210___
rdf:type
n13:Vysledek skos:Concept
dcterms:description
The objective of this work was to study the mechanism of liver parenchyma development under the influence of restriction of diet. Useful information is presented about the pathologic features associated with diet restriction in a chicken animal model of NAFLD. Hepatocyte diameter was significantly influenced by sex, genotype, and the experimental group. The proportion of interstitial tissue to the liver parenchyma was highly influenced by genotype and group, but there were no interactions. An increase in the steatosis histologic grade is associated with inflammatory changes, with decrease of hepatocyte diameter and with a decreasing proportion of interstitial tissue to the liver parenchyma. The results show that early restriction is not associated with the development of fibrosis of the liver tissue. The objective of this work was to study the mechanism of liver parenchyma development under the influence of restriction of diet. Useful information is presented about the pathologic features associated with diet restriction in a chicken animal model of NAFLD. Hepatocyte diameter was significantly influenced by sex, genotype, and the experimental group. The proportion of interstitial tissue to the liver parenchyma was highly influenced by genotype and group, but there were no interactions. An increase in the steatosis histologic grade is associated with inflammatory changes, with decrease of hepatocyte diameter and with a decreasing proportion of interstitial tissue to the liver parenchyma. The results show that early restriction is not associated with the development of fibrosis of the liver tissue.
dcterms:title
Experimental study of non-alcoholic fatty liver disease (NAFLD) on a model of starving chickens: Is generalization of steatosis accompanied by fibrosis of the liver tissue? Experimental study of non-alcoholic fatty liver disease (NAFLD) on a model of starving chickens: Is generalization of steatosis accompanied by fibrosis of the liver tissue?
skos:prefLabel
Experimental study of non-alcoholic fatty liver disease (NAFLD) on a model of starving chickens: Is generalization of steatosis accompanied by fibrosis of the liver tissue? Experimental study of non-alcoholic fatty liver disease (NAFLD) on a model of starving chickens: Is generalization of steatosis accompanied by fibrosis of the liver tissue?
skos:notation
RIV/60460709:41210/11:50330!RIV12-MSM-41210___
n13:predkladatel
n18:orjk%3A41210
n3:aktivita
n10:Z
n3:aktivity
Z(MSM6046070901)
n3:cisloPeriodika
3
n3:dodaniDat
n6:2012
n3:domaciTvurceVysledku
n7:4064135 n7:8783004 n7:9349618 n7:3761207
n3:druhVysledku
n14:J
n3:duvernostUdaju
n9:S
n3:entitaPredkladatele
n16:predkladatel
n3:idSjednocenehoVysledku
198819
n3:idVysledku
RIV/60460709:41210/11:50330
n3:jazykVysledku
n19:eng
n3:klicovaSlova
hyperaemia, lipids, metabolism, NASH, nutrition, restriction, starvation
n3:klicoveSlovo
n8:hyperaemia n8:lipids n8:metabolism n8:nutrition n8:restriction n8:starvation n8:NASH
n3:kodStatuVydavatele
DE - Spolková republika Německo
n3:kontrolniKodProRIV
[C030942C2794]
n3:nazevZdroje
Pathology Research and Practice
n3:obor
n11:GG
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
5
n3:rokUplatneniVysledku
n6:2011
n3:svazekPeriodika
207
n3:tvurceVysledku
Vodková, Zuzana Rajmon, Radko Tůmová, Eva Makovický, Peter Dudová, Markéta
n3:wos
0
n3:zamer
n15:MSM6046070901
s:issn
0344-0338
s:numberOfPages
5
n17:organizacniJednotka
41210