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Statements

Subject Item
n2:RIV%2F60162694%3AG44__%2F13%3A43874937%21RIV14-MZ0-G44_____
rdf:type
n12:Vysledek skos:Concept
rdfs:seeAlso
http://www.ingentaconnect.com/content/ben/mrmc/2013/00000013/00000014/art00011
dcterms:description
Treatment of intoxications caused by nerve agents and organophosphorus pesticides consists of different approaches. The first approach is called prophylaxis or pre-exposure administration of antidotes such as cholinesterase reactivators or bioscavengers. The second, post-exposure treatment consists of anticholinergic drugs, acetylcholinesterase reactivators and anticonvulsants. This article is aimed at both mentioned approaches, especially focused on cholinesterase reactivators, which are a broad group of structurally different compounds that can be used in prophylaxis (separately or in combination with butyrylcholinesterase) and also as post-exposure treatment. Treatment of intoxications caused by nerve agents and organophosphorus pesticides consists of different approaches. The first approach is called prophylaxis or pre-exposure administration of antidotes such as cholinesterase reactivators or bioscavengers. The second, post-exposure treatment consists of anticholinergic drugs, acetylcholinesterase reactivators and anticonvulsants. This article is aimed at both mentioned approaches, especially focused on cholinesterase reactivators, which are a broad group of structurally different compounds that can be used in prophylaxis (separately or in combination with butyrylcholinesterase) and also as post-exposure treatment.
dcterms:title
Prophylaxis and post-exposure treatment of intoxications caused by nerve agents and organophosphorus pesticides Prophylaxis and post-exposure treatment of intoxications caused by nerve agents and organophosphorus pesticides
skos:prefLabel
Prophylaxis and post-exposure treatment of intoxications caused by nerve agents and organophosphorus pesticides Prophylaxis and post-exposure treatment of intoxications caused by nerve agents and organophosphorus pesticides
skos:notation
RIV/60162694:G44__/13:43874937!RIV14-MZ0-G44_____
n3:aktivita
n13:I n13:P
n3:aktivity
I, P(LH13009), P(NT12062)
n3:cisloPeriodika
14
n3:dodaniDat
n9:2014
n3:domaciTvurceVysledku
n14:3876284 n14:4185137
n3:druhVysledku
n18:J
n3:duvernostUdaju
n20:S
n3:entitaPredkladatele
n19:predkladatel
n3:idSjednocenehoVysledku
100407
n3:idVysledku
RIV/60162694:G44__/13:43874937
n3:jazykVysledku
n11:eng
n3:klicovaSlova
toxicity; oxime; protection; reactivator; organophosphate; antidote; treatment; prophylaxis; poisoning; pesticides; nerve agents; butyrylcholinesterase; Acetylcholinesterase
n3:klicoveSlovo
n5:pesticides n5:nerve%20agents n5:oxime n5:organophosphate n5:butyrylcholinesterase n5:treatment n5:poisoning n5:reactivator n5:protection n5:Acetylcholinesterase n5:prophylaxis n5:toxicity n5:antidote
n3:kodStatuVydavatele
AE - Stát Spojené arabské emiráty
n3:kontrolniKodProRIV
[1C56BC9A74CE]
n3:nazevZdroje
Mini Reviews in Medicinal Chemistry
n3:obor
n17:FR
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
6
n3:projekt
n4:NT12062 n4:LH13009
n3:rokUplatneniVysledku
n9:2013
n3:svazekPeriodika
13
n3:tvurceVysledku
Musílek, Kamil Žďárová Karasová, Jana Kuča, Kamil Pohanka, Miroslav Soukup, Ondřej Jun, Daniel
n3:wos
000328088300011
s:issn
1389-5575
s:numberOfPages
14
n7:doi
10.2174/13895575113136660108
n6:organizacniJednotka
G44