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Statements

Subject Item
n2:RIV%2F60162694%3AG44__%2F12%3A43875339%21RIV15-MO0-G44_____
rdf:type
n6:Vysledek skos:Concept
rdfs:seeAlso
http://poj.peeters-leuven.be/content.php?url=issue&journal_code=AC&issue=3&vol=67
dcterms:description
Objective The objective of this study was to assess the mid-term effects of cardiac resynchronization therapy on systolic function and remodelling of the right ventricle in clinical responders and non-responders. Methods A biventricular system was implanted between July 2005 and May 2008 in 58 patients with heart failure NYHA class II-IV. At baseline, three and 15 months after implantation, the following parameters were determined: NYHA class, quality of life, six-minute walk test, echocardiography including assessment of right ventricular systolic function by tricuspid annular plane systolic excursion and by pulsed tissue Doppler imaging (myocardial peak systolic velocity was measured at the tricuspid annulus). We also assessed the presence of ventricular dyssynchrony. Results There were no significant changes after three months of cardiac resynchronization therapy on right ventricular systolic function and remodelling in responders and non-responders. Among responders, we found a statistically significant improvement of right ventricular systolic function and also a significant decrease in the size of the right ventricle after 15 months of therapy (systolic excursion before therapy 17.8 +/- 4.0 mm vs 19.4 +/- 3.7 mm, P < 0.05, after therapy; peak systolic velocity initially 11.9 +/- 2.9 cm/s vs 12.7 +/- 3.2 cm/s; right ventricle size before therapy 29.3 +/- 5.0 mm vs 27.8 +/- 4.2 mm, P < 0.05, after therapy. These changes were not observed in non-responders. Conclusions Fifteen months after cardiac resynchronization therapy, we found a statistically significant improvement of right ventricular systolic function and a significant reduction of right ventricular size in responders to cardiac resynchronization therapy. Objective The objective of this study was to assess the mid-term effects of cardiac resynchronization therapy on systolic function and remodelling of the right ventricle in clinical responders and non-responders. Methods A biventricular system was implanted between July 2005 and May 2008 in 58 patients with heart failure NYHA class II-IV. At baseline, three and 15 months after implantation, the following parameters were determined: NYHA class, quality of life, six-minute walk test, echocardiography including assessment of right ventricular systolic function by tricuspid annular plane systolic excursion and by pulsed tissue Doppler imaging (myocardial peak systolic velocity was measured at the tricuspid annulus). We also assessed the presence of ventricular dyssynchrony. Results There were no significant changes after three months of cardiac resynchronization therapy on right ventricular systolic function and remodelling in responders and non-responders. Among responders, we found a statistically significant improvement of right ventricular systolic function and also a significant decrease in the size of the right ventricle after 15 months of therapy (systolic excursion before therapy 17.8 +/- 4.0 mm vs 19.4 +/- 3.7 mm, P < 0.05, after therapy; peak systolic velocity initially 11.9 +/- 2.9 cm/s vs 12.7 +/- 3.2 cm/s; right ventricle size before therapy 29.3 +/- 5.0 mm vs 27.8 +/- 4.2 mm, P < 0.05, after therapy. These changes were not observed in non-responders. Conclusions Fifteen months after cardiac resynchronization therapy, we found a statistically significant improvement of right ventricular systolic function and a significant reduction of right ventricular size in responders to cardiac resynchronization therapy.
dcterms:title
Cardiac resynchronization therapy in clinical responders: right ventricular echocardiographic changes at mid-term follow-up Cardiac resynchronization therapy in clinical responders: right ventricular echocardiographic changes at mid-term follow-up
skos:prefLabel
Cardiac resynchronization therapy in clinical responders: right ventricular echocardiographic changes at mid-term follow-up Cardiac resynchronization therapy in clinical responders: right ventricular echocardiographic changes at mid-term follow-up
skos:notation
RIV/60162694:G44__/12:43875339!RIV15-MO0-G44_____
n3:aktivita
n9:I n9:V
n3:aktivity
I, V
n3:cisloPeriodika
3
n3:dodaniDat
n14:2015
n3:domaciTvurceVysledku
n18:3474437 n18:6300812
n3:druhVysledku
n7:J
n3:duvernostUdaju
n15:S
n3:entitaPredkladatele
n17:predkladatel
n3:idSjednocenehoVysledku
125994
n3:idVysledku
RIV/60162694:G44__/12:43875339
n3:jazykVysledku
n8:eng
n3:klicovaSlova
ventricular dyssynchrony; right ventricle; echocardiography; heart failure; Cardiac resynchronization therapy
n3:klicoveSlovo
n4:right%20ventricle n4:ventricular%20dyssynchrony n4:echocardiography n4:Cardiac%20resynchronization%20therapy n4:heart%20failure
n3:kodStatuVydavatele
BE - Belgické království
n3:kontrolniKodProRIV
[6D19BE1D210C]
n3:nazevZdroje
Acta Cardiologica
n3:obor
n19:FA
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
5
n3:rokUplatneniVysledku
n14:2012
n3:svazekPeriodika
67
n3:tvurceVysledku
Praus, Rudolf Haman, Luděk Bláha, Václav Tauchman, Miloslav Pařízek, Petr
n3:wos
000305814400007
s:issn
0001-5385
s:numberOfPages
6
n12:doi
10.2143/AC.67.3.2160720
n16:organizacniJednotka
G44