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Statements

Subject Item
n2:RIV%2F60162694%3AG44__%2F12%3A43874685%21RIV13-MO0-G44_____
rdf:type
n9:Vysledek skos:Concept
rdfs:seeAlso
http://www.springer.com/?SGWID=0-102-24-0-0&sortOrder=relevance&searchType=EASY_CDA&searchScope=onlinecontent&queryText=the+effect+of+somatostatin+and+its+analogs+in+the+prevention+of+pancreatic+fistula+after+elective+pancreatic+surgery
dcterms:description
Background: The prophylactic use of somatostatin and its analogs has been suggested to lower the rate of pancreatic fistula. The aim of this review is to discuss the results of published randomized trials and meta-analyses studying the effect of somatostatin and its analogs. Methods: We performed a Medline search for prospective randomized trials, systematic reviews and meta-analyses with regard to the prophylactic use of somatostatin and its analogs. Results: Eleven randomized trials and six meta-analyses were identified. The randomized trials differ in terms of study designs, diagnosis, operative procedures, drug dosage, time of administration, and the pancreatic fistula definition; therefore, it is advisable to carefully interpret the results of the individual randomized trials. Conclusion: The routine administration of somatostatin and its analogs in elective pancreatic surgery cannot be recommended. However, selective administration is advisable in cases which carry significantly higher risk of developing pancreatic fistula. Background: The prophylactic use of somatostatin and its analogs has been suggested to lower the rate of pancreatic fistula. The aim of this review is to discuss the results of published randomized trials and meta-analyses studying the effect of somatostatin and its analogs. Methods: We performed a Medline search for prospective randomized trials, systematic reviews and meta-analyses with regard to the prophylactic use of somatostatin and its analogs. Results: Eleven randomized trials and six meta-analyses were identified. The randomized trials differ in terms of study designs, diagnosis, operative procedures, drug dosage, time of administration, and the pancreatic fistula definition; therefore, it is advisable to carefully interpret the results of the individual randomized trials. Conclusion: The routine administration of somatostatin and its analogs in elective pancreatic surgery cannot be recommended. However, selective administration is advisable in cases which carry significantly higher risk of developing pancreatic fistula.
dcterms:title
The effect of somatostatin and its analogs in the prevention of pancreatic fistula after elective pancreatic surgery The effect of somatostatin and its analogs in the prevention of pancreatic fistula after elective pancreatic surgery
skos:prefLabel
The effect of somatostatin and its analogs in the prevention of pancreatic fistula after elective pancreatic surgery The effect of somatostatin and its analogs in the prevention of pancreatic fistula after elective pancreatic surgery
skos:notation
RIV/60162694:G44__/12:43874685!RIV13-MO0-G44_____
n3:aktivita
n14:I n14:V
n3:aktivity
I, V
n3:cisloPeriodika
2
n3:dodaniDat
n16:2013
n3:domaciTvurceVysledku
n11:7812213
n3:druhVysledku
n15:J
n3:duvernostUdaju
n18:S
n3:entitaPredkladatele
n4:predkladatel
n3:idSjednocenehoVysledku
133267
n3:idVysledku
RIV/60162694:G44__/12:43874685
n3:jazykVysledku
n8:eng
n3:klicovaSlova
postoperative complications; pancreatic fistula; pancreatic surgery; octreotide; somatostatin
n3:klicoveSlovo
n6:octreotide n6:somatostatin n6:postoperative%20complications n6:pancreatic%20fistula n6:pancreatic%20surgery
n3:kodStatuVydavatele
AT - Rakouská republika
n3:kontrolniKodProRIV
[16CFBDC4B98C]
n3:nazevZdroje
European Surgery
n3:obor
n17:FJ
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
4
n3:rokUplatneniVysledku
n16:2012
n3:svazekPeriodika
44
n3:tvurceVysledku
Jon, Bohumil Šubrt, Zdeněk Čečka, Filip Ferko, Alexander
n3:wos
000304610000008
s:issn
1682-8631
s:numberOfPages
10
n10:doi
10.1007/s10353-011-0612-z
n13:organizacniJednotka
G44