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Statements

Subject Item
n2:RIV%2F60162694%3AG44__%2F11%3A00002448%21RIV12-MSM-G44_____
rdf:type
skos:Concept n15:Vysledek
rdfs:seeAlso
http://www.intechopen.com/articles/show/title/progress-in-antidotes-acetylcholinesterase-reactivators-against-organophosphorus-pesticides
dcterms:description
During the last two decades, the treatment of organophosphate pesticide (OPP) exposure became more discussed regarding the growing agricultural production, industrial and suicidal means. In this chapter is summarised the design, evaluation and structure-activity relationship studies of recently produced AChE reactivators. Since pralidoxime, many oximes have been produced or tested against OPP poisoning, and several novel compounds show very promising abilities as comparable (or higher) to commercial oximes. Some of these are highlighted for their further testing of OPP exposure, and additionally, the main structure-activity relationship of AChE reactivators against OPP are discussed. During the last two decades, the treatment of organophosphate pesticide (OPP) exposure became more discussed regarding the growing agricultural production, industrial and suicidal means. In this chapter is summarised the design, evaluation and structure-activity relationship studies of recently produced AChE reactivators. Since pralidoxime, many oximes have been produced or tested against OPP poisoning, and several novel compounds show very promising abilities as comparable (or higher) to commercial oximes. Some of these are highlighted for their further testing of OPP exposure, and additionally, the main structure-activity relationship of AChE reactivators against OPP are discussed.
dcterms:title
Progress in antidotes (acetylcholinesterase reactivators) against organophosphorus pesticides Progress in antidotes (acetylcholinesterase reactivators) against organophosphorus pesticides
skos:prefLabel
Progress in antidotes (acetylcholinesterase reactivators) against organophosphorus pesticides Progress in antidotes (acetylcholinesterase reactivators) against organophosphorus pesticides
skos:notation
RIV/60162694:G44__/11:00002448!RIV12-MSM-G44_____
n3:aktivita
n14:P
n3:aktivity
P(ME09086)
n3:dodaniDat
n6:2012
n3:domaciTvurceVysledku
n5:4898737 n5:4185137 n5:6306888 n5:6469922 n5:3876284 n5:8581223
n3:druhVysledku
n18:C
n3:duvernostUdaju
n8:S
n3:entitaPredkladatele
n10:predkladatel
n3:idSjednocenehoVysledku
224467
n3:idVysledku
RIV/60162694:G44__/11:00002448
n3:jazykVysledku
n20:eng
n3:klicovaSlova
acetylcholinesterase; pesticide; insecticide; reactivation; oxime; SAR
n3:klicoveSlovo
n13:reactivation n13:pesticide n13:acetylcholinesterase n13:insecticide n13:oxime n13:SAR
n3:kontrolniKodProRIV
[528728FBDD18]
n3:mistoVydani
Rijeka
n3:nazevZdroje
Pesticides in the modern world - Effects of pesticides exposure
n3:obor
n9:FR
n3:pocetDomacichTvurcuVysledku
6
n3:pocetStranKnihy
376
n3:pocetTvurcuVysledku
7
n3:projekt
n21:ME09086
n3:rokUplatneniVysledku
n6:2011
n3:tvurceVysledku
Musílek, Kamil Žďárová Karasová, Jana Jun, Daniel Pohanka, Miroslav Holas, Ondřej Horová, Anna Kuča, Kamil
s:numberOfPages
18
n19:hasPublisher
Intech
n16:isbn
978-953-307-454-2
n12:organizacniJednotka
G44