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Statements

Subject Item
n2:RIV%2F60162694%3AG44__%2F10%3A00002409%21RIV11-MO0-G44_____
rdf:type
n12:Vysledek skos:Concept
dcterms:description
The aim of this study was to evaluate the diagnostic yield of capsule endoscopy in nonsteroidal anti-inflammatory drug (NSAID)-induced enteropathy in pigs. Indomethacin (400 mg/day) was administered orally for 10 days to eight female pigs. Afterwards, capsule endoscopy was performed, using the EndoCapsule system (OlympusOpticalCo., Tokyo, Japan). The following morning, pharmacological euthanasia and immediate autopsy were performed. Small bowel injury compatible with NSAID-induced enteropathy was observed in 7/8 animals. The most common lesions were red spots and erosions. Ulcers and small intestinal bleeding were identified sporadically. Sensitivity and specificity of capsule endoscopy were 83.3% and 95.8%, respectively. Our results indicate that wireless capsule endoscopy is a highly accurate noninvasive method for evaluation of experimental NSAID-induced enteropathy.10.1007/s10620-009-1066-z The aim of this study was to evaluate the diagnostic yield of capsule endoscopy in nonsteroidal anti-inflammatory drug (NSAID)-induced enteropathy in pigs. Indomethacin (400 mg/day) was administered orally for 10 days to eight female pigs. Afterwards, capsule endoscopy was performed, using the EndoCapsule system (OlympusOpticalCo., Tokyo, Japan). The following morning, pharmacological euthanasia and immediate autopsy were performed. Small bowel injury compatible with NSAID-induced enteropathy was observed in 7/8 animals. The most common lesions were red spots and erosions. Ulcers and small intestinal bleeding were identified sporadically. Sensitivity and specificity of capsule endoscopy were 83.3% and 95.8%, respectively. Our results indicate that wireless capsule endoscopy is a highly accurate noninvasive method for evaluation of experimental NSAID-induced enteropathy.10.1007/s10620-009-1066-z
dcterms:title
Wireless capsule endoscopy in enteropathy induced by nonsteroidal anti-inflammatory drugs in pigs Wireless capsule endoscopy in enteropathy induced by nonsteroidal anti-inflammatory drugs in pigs
skos:prefLabel
Wireless capsule endoscopy in enteropathy induced by nonsteroidal anti-inflammatory drugs in pigs Wireless capsule endoscopy in enteropathy induced by nonsteroidal anti-inflammatory drugs in pigs
skos:notation
RIV/60162694:G44__/10:00002409!RIV11-MO0-G44_____
n3:aktivita
n11:P n11:I n11:V n11:Z
n3:aktivity
I, P(GA305/08/0535), V, Z(MZ0FNHK2005)
n3:cisloPeriodika
9
n3:dodaniDat
n7:2011
n3:domaciTvurceVysledku
n6:8216789 n6:7741456 n6:4404394
n3:druhVysledku
n9:J
n3:duvernostUdaju
n5:S
n3:entitaPredkladatele
n18:predkladatel
n3:idSjednocenehoVysledku
298865
n3:idVysledku
RIV/60162694:G44__/10:00002409
n3:jazykVysledku
n15:eng
n3:klicovaSlova
experimental pigs; enteroscopy; capsule endoscopy; nonsteroidal anti-inflammatory drugs; indomethacin; NSAID-induced enteropathy
n3:klicoveSlovo
n4:indomethacin n4:nonsteroidal%20anti-inflammatory%20drugs n4:enteroscopy n4:capsule%20endoscopy n4:NSAID-induced%20enteropathy n4:experimental%20pigs
n3:kodStatuVydavatele
NL - Nizozemsko
n3:kontrolniKodProRIV
[50F03CB02EDC]
n3:nazevZdroje
Digestive Diseases and Sciences
n3:obor
n10:FE
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
9
n3:projekt
n17:GA305%2F08%2F0535
n3:rokUplatneniVysledku
n7:2010
n3:svazekPeriodika
55
n3:tvurceVysledku
Bureš, Jan Kuneš, Martin Tachecí, Ilja Österreicher, Jan Kopáčová, M. Pejchal, Jaroslav Květina, Jaroslav Reichert, Stanislav Špelda, Stanislav
n3:wos
000280595500008
n3:zamer
n14:MZ0FNHK2005
s:issn
0163-2116
s:numberOfPages
7
n16:organizacniJednotka
G44