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Statements

Subject Item
n2:RIV%2F60162694%3AG44__%2F10%3A00002276%21RIV11-MO0-G44_____
rdf:type
n13:Vysledek skos:Concept
dcterms:description
While the ability to reduce tabun-induced acute neurotoxicity of obidoxime and K203 was similar, the neuroprotective efficacy of KR-22836 was slightly higher. Thus, the newly developed fluorinated analogue of K203, called KR-22836, is able to slightly increase the neuroprotective effectiveness of antidotal treatment of acute tabun poisonings compared to K203 and currently available obidoxime While the ability to reduce tabun-induced acute neurotoxicity of obidoxime and K203 was similar, the neuroprotective efficacy of KR-22836 was slightly higher. Thus, the newly developed fluorinated analogue of K203, called KR-22836, is able to slightly increase the neuroprotective effectiveness of antidotal treatment of acute tabun poisonings compared to K203 and currently available obidoxime
dcterms:title
A comparison of neuroprotective efficacy of the oxime K203 and its fluorinated analogue (KR-22836) with obidoxime in tabun-poisoned rats A comparison of neuroprotective efficacy of the oxime K203 and its fluorinated analogue (KR-22836) with obidoxime in tabun-poisoned rats
skos:prefLabel
A comparison of neuroprotective efficacy of the oxime K203 and its fluorinated analogue (KR-22836) with obidoxime in tabun-poisoned rats A comparison of neuroprotective efficacy of the oxime K203 and its fluorinated analogue (KR-22836) with obidoxime in tabun-poisoned rats
skos:notation
RIV/60162694:G44__/10:00002276!RIV11-MO0-G44_____
n3:aktivita
n17:Z
n3:aktivity
Z(MO0FVZ0000501)
n3:cisloPeriodika
5
n3:dodaniDat
n15:2011
n3:domaciTvurceVysledku
n4:6306888 n4:6469922 n4:2182262 n4:4898737
n3:druhVysledku
n18:J
n3:duvernostUdaju
n16:S
n3:entitaPredkladatele
n11:predkladatel
n3:idSjednocenehoVysledku
244531
n3:idVysledku
RIV/60162694:G44__/10:00002276
n3:jazykVysledku
n12:eng
n3:klicovaSlova
Functional observatory battery; neurotoxicity; K203; KR-22836; obidoxime; tabun
n3:klicoveSlovo
n14:obidoxime n14:KR-22836 n14:tabun n14:neurotoxicity n14:K203 n14:Functional%20observatory%20battery
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[050E00CA9B47]
n3:nazevZdroje
Basic & Clinical Pharmacology & Toxicology
n3:obor
n9:FP
n3:pocetDomacichTvurcuVysledku
4
n3:pocetTvurcuVysledku
6
n3:rokUplatneniVysledku
n15:2010
n3:svazekPeriodika
107
n3:tvurceVysledku
Jung, Young-Sik Musílek, Kamil Tesařová, Sandra Kassa, Jiří Kuča, Kamil Žďárová Karasová, Jana
n3:wos
000283093100003
n3:zamer
n5:MO0FVZ0000501
s:issn
1742-7835
s:numberOfPages
7
n10:organizacniJednotka
G44