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Statements

Subject Item
n2:RIV%2F60162694%3AG44__%2F09%3A00002117%21RIV10-MO0-G44_____
rdf:type
n5:Vysledek skos:Concept
dcterms:description
Pharmacological prophylaxis against nerve agentss and organophosphates is described. Approaches can be different: it is protection of acetylcholinesterase against inhibition when reversíble cholinesterase inhibitors are used (pyridostigmine). Its higher dose has side effect that can be eliminated by administration of anticholinergics (prophylactic antidote PANPAL). The treatment in advance comprises administration of reactivator HI-6 (TRANSANT). Administration of scavengers (cholinesterases, Protexia) decreases the level of toxic agent. The use of other drugs (huperzin A) is another possibility. Pharmacological prophylaxis against nerve agentss and organophosphates is described. Approaches can be different: it is protection of acetylcholinesterase against inhibition when reversíble cholinesterase inhibitors are used (pyridostigmine). Its higher dose has side effect that can be eliminated by administration of anticholinergics (prophylactic antidote PANPAL). The treatment in advance comprises administration of reactivator HI-6 (TRANSANT). Administration of scavengers (cholinesterases, Protexia) decreases the level of toxic agent. The use of other drugs (huperzin A) is another possibility.
dcterms:title
Pharmacological prophylaxis against nerve agent poisoning: experimental studies and practical implications Pharmacological prophylaxis against nerve agent poisoning: experimental studies and practical implications
skos:prefLabel
Pharmacological prophylaxis against nerve agent poisoning: experimental studies and practical implications Pharmacological prophylaxis against nerve agent poisoning: experimental studies and practical implications
skos:notation
RIV/60162694:G44__/09:00002117!RIV10-MO0-G44_____
n3:aktivita
n9:Z
n3:aktivity
Z(MO0FVZ0000501)
n3:dodaniDat
n15:2010
n3:domaciTvurceVysledku
n11:7844581 n11:6306888 n11:4488695 n11:4185137 n11:2182262
n3:druhVysledku
n18:C
n3:duvernostUdaju
n6:S
n3:entitaPredkladatele
n7:predkladatel
n3:idSjednocenehoVysledku
333256
n3:idVysledku
RIV/60162694:G44__/09:00002117
n3:jazykVysledku
n14:eng
n3:klicovaSlova
nerve agents; prophylaxis; butyrylcholinesterase; practical means exposure; low-level exposure; hippocampus
n3:klicoveSlovo
n8:butyrylcholinesterase n8:hippocampus n8:low-level%20exposure n8:prophylaxis n8:practical%20means%20exposure n8:nerve%20agents
n3:kontrolniKodProRIV
[33EDEAFF3D07]
n3:mistoVydani
San Diego
n3:nazevZdroje
Handbook of toxicology of chemical warfare agents
n3:obor
n13:FP
n3:pocetDomacichTvurcuVysledku
5
n3:pocetStranKnihy
1168
n3:pocetTvurcuVysledku
5
n3:rokUplatneniVysledku
n15:2009
n3:tvurceVysledku
Bajgar, Jiří Kuča, Kamil Fusek, Josef Jun, Daniel Kassa, Jiří
n3:zamer
n16:MO0FVZ0000501
s:numberOfPages
10
n19:hasPublisher
Acad Press Elsevier Sci
n20:isbn
978-0-12-374484-5
n17:organizacniJednotka
G44