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Statements

Subject Item
n2:RIV%2F60162694%3AG44__%2F08%3A00001930%21RIV09-GA0-G44_____
rdf:type
n18:Vysledek skos:Concept
dcterms:description
The pharmacokinetics of K-203, a recently synthesized bis-pyridinium aldoxime, have been investigated by reversed-phase HPLC. The K-203 content of serum samples was monitored by HPLC with ultraviolet absorbance detection at 286 nm. The low concentration of K-203 in samples of brain, eyes, and cerebrospinal fluid was also determined by HPLC; quantitative evaluation was possible by use of an amperometric detector. Farmakokinetika látky K203 - v současnosti syntetizovaného bispyridiniového oximu - byla zkoumána pomocí RP-HPLC. K203 obsah sérových vzorků bylo monitorováno pomocí HPLC-UV při 286 nm. Nízká koncentrace K203 ve vzorcích mozku, očí a cerebrospinální tekutiny byly rovněž určeny. Kvantitativní zhodnocení bylo umožněno amperometrickým detektorem. The pharmacokinetics of K-203, a recently synthesized bis-pyridinium aldoxime, have been investigated by reversed-phase HPLC. The K-203 content of serum samples was monitored by HPLC with ultraviolet absorbance detection at 286 nm. The low concentration of K-203 in samples of brain, eyes, and cerebrospinal fluid was also determined by HPLC; quantitative evaluation was possible by use of an amperometric detector.
dcterms:title
HPLC study of the pharmacokinetics of K-203 HPLC study of the pharmacokinetics of K-203 HPLC studie farmakokinetiky látky K-203
skos:prefLabel
HPLC studie farmakokinetiky látky K-203 HPLC study of the pharmacokinetics of K-203 HPLC study of the pharmacokinetics of K-203
skos:notation
RIV/60162694:G44__/08:00001930!RIV09-GA0-G44_____
n3:aktivita
n12:P
n3:aktivity
P(GP305/07/P162)
n3:cisloPeriodika
4
n3:dodaniDat
n6:2009
n3:domaciTvurceVysledku
n11:6469922 n11:6306888
n3:druhVysledku
n13:J
n3:duvernostUdaju
n8:S
n3:entitaPredkladatele
n14:predkladatel
n3:idSjednocenehoVysledku
370773
n3:idVysledku
RIV/60162694:G44__/08:00001930
n3:jazykVysledku
n16:eng
n3:klicovaSlova
HPLC; K-203; pharmacokinetics; serum; brain; CSF; eyes
n3:klicoveSlovo
n9:CSF n9:HPLC n9:K-203 n9:eyes n9:serum n9:pharmacokinetics n9:brain
n3:kodStatuVydavatele
PL - Polská republika
n3:kontrolniKodProRIV
[9F80A8817A51]
n3:nazevZdroje
Acta Chromatographica
n3:obor
n15:FP
n3:pocetDomacichTvurcuVysledku
2
n3:pocetTvurcuVysledku
6
n3:projekt
n7:GP305%2F07%2FP162
n3:rokUplatneniVysledku
n6:2008
n3:svazekPeriodika
20
n3:tvurceVysledku
Tekes, K. Szegi, P. Kalasz, H. Kuča, Kamil Musílek, Kamil Laufer, L.
s:issn
1233-2356
s:numberOfPages
10
n17:organizacniJednotka
G44