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Statements

Subject Item
n2:RIV%2F60162694%3AG38__%2F04%3A00001075%21RIV%2F2005%2FMO0%2FG38005%2FN
rdf:type
skos:Concept n16:Vysledek
dcterms:description
The interaction of seventeen heteroarenium salts with the enzyme acetylcholinesterase was investigated using in vitro experiments. Rat brains were used as a source of the enzyme. All compounds involved in this study were found to be competitive acetylcholinesterase inhibitors. 10-methyl-acridinium iodide seems to be the most potent acetylcholinesterase inhibitor. The interaction of seventeen heteroarenium salts with the enzyme acetylcholinesterase was investigated using in vitro experiments. Rat brains were used as a source of the enzyme. All compounds involved in this study were found to be competitive acetylcholinesterase inhibitors. 10-methyl-acridinium iodide seems to be the most potent acetylcholinesterase inhibitor. Kvartérní heteroareniové soli jako kompetitivní inhibitory mozkové acetylcholinesterázy
dcterms:title
Quaternary heteroarenium salts as the competitive inhibitors of the brain acetylcholinesterase Quaternary heteroarenium salts as the competitive inhibitors of the brain acetylcholinesterase Kvartérní heteroareniové soli jako kompetitivní inhibitory mozkové acetylcholinesterázy
skos:prefLabel
Kvartérní heteroareniové soli jako kompetitivní inhibitory mozkové acetylcholinesterázy Quaternary heteroarenium salts as the competitive inhibitors of the brain acetylcholinesterase Quaternary heteroarenium salts as the competitive inhibitors of the brain acetylcholinesterase
skos:notation
RIV/60162694:G38__/04:00001075!RIV/2005/MO0/G38005/N
n3:strany
97-100
n3:aktivita
n10:P
n3:aktivity
P(ONVLAJEP20031)
n3:cisloPeriodika
2
n3:dodaniDat
n8:2005
n3:domaciTvurceVysledku
n9:5211336 n9:3691314 n9:6306888
n3:druhVysledku
n12:J
n3:duvernostUdaju
n17:S
n3:entitaPredkladatele
n18:predkladatel
n3:idSjednocenehoVysledku
583386
n3:idVysledku
RIV/60162694:G38__/04:00001075
n3:jazykVysledku
n13:eng
n3:klicovaSlova
acetylcholinesterase;heteroarenium salts;inhibition;reactivation;Alzheimer´s disease
n3:klicoveSlovo
n5:heteroarenium%20salts n5:inhibition n5:Alzheimer%C2%B4s%20disease n5:reactivation n5:acetylcholinesterase
n3:kodStatuVydavatele
AE - Stát Spojené arabské emiráty
n3:kontrolniKodProRIV
[8AB04F7C3177]
n3:nazevZdroje
Letters in Drug Design and Discovery
n3:obor
n7:FP
n3:pocetDomacichTvurcuVysledku
3
n3:pocetTvurcuVysledku
4
n3:projekt
n15:ONVLAJEP20031
n3:rokUplatneniVysledku
n8:2004
n3:svazekPeriodika
1
n3:tvurceVysledku
Kuča, Kamil Cabal, Jiří Patočka, Jiří Dohnal, Vlastimil
s:issn
1570-1808
s:numberOfPages
4
n14:organizacniJednotka
G38