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Statements

Subject Item
n2:RIV%2F60077395%3A_____%2F04%3A00100912%21RIV%2F2005%2FAV0%2FA60005%2FN
rdf:type
n12:Vysledek skos:Concept
dcterms:description
Metabolism of paclitaxel and docetaxel of cytochrome P450 was compared in humans, pigs, minipigs and rats. While docetaxel metabolism is the same in all four compared species, metabolism of paclitaxel showed differences, especially in 6alpha-hydroxypaclitaxel present exclusively in humans. Byl porovnán metabolismus paclitaxelu a docetaxelu cytochromy P450 u člověka, prasete, miniprasete a krysy. Zatímco metabolismus docetaxelu je stejný u všech čtyř zkoumaných druhů, metabolismus paclitaxelu vykazuje rozdíly, zejména v 6?-hydroxypaclitaxelu přítomnému výlučně u člověka. Metabolism of paclitaxel and docetaxel of cytochrome P450 was compared in humans, pigs, minipigs and rats. While docetaxel metabolism is the same in all four compared species, metabolism of paclitaxel showed differences, especially in 6alpha-hydroxypaclitaxel present exclusively in humans.
dcterms:title
Different in vitro metabolism of paclitaxel and docetaxel in humans, rats, pigs, and minipigs Different in vitro metabolism of paclitaxel and docetaxel in humans, rats, pigs, and minipigs Rozdílný metabolismus paclitaxelu a docetaxelu u člověka, krysy, prasete a minprasete
skos:prefLabel
Different in vitro metabolism of paclitaxel and docetaxel in humans, rats, pigs, and minipigs Different in vitro metabolism of paclitaxel and docetaxel in humans, rats, pigs, and minipigs Rozdílný metabolismus paclitaxelu a docetaxelu u člověka, krysy, prasete a minprasete
skos:notation
RIV/60077395:_____/04:00100912!RIV/2005/AV0/A60005/N
n3:strany
666;674
n3:aktivita
n8:P n8:Z
n3:aktivity
P(GA203/02/1152), P(NL6715), P(NL7567), Z(AV0Z5007907)
n3:cisloPeriodika
6
n3:dodaniDat
n5:2005
n3:domaciTvurceVysledku
n15:8519064
n3:druhVysledku
n4:J
n3:duvernostUdaju
n13:S
n3:entitaPredkladatele
n11:predkladatel
n3:idSjednocenehoVysledku
560557
n3:idVysledku
RIV/60077395:_____/04:00100912
n3:jazykVysledku
n6:eng
n3:klicovaSlova
human-liver microsomes;human cytochromes P450
n3:klicoveSlovo
n17:human%20cytochromes%20P450 n17:human-liver%20microsomes
n3:kodStatuVydavatele
US - Spojené státy americké
n3:kontrolniKodProRIV
[EED831EEC236]
n3:nazevZdroje
Drug Metabolism and Disposition
n3:obor
n18:CE
n3:pocetDomacichTvurcuVysledku
1
n3:pocetTvurcuVysledku
7
n3:projekt
n10:GA203%2F02%2F1152 n10:NL6715 n10:NL7567
n3:rokUplatneniVysledku
n5:2004
n3:svazekPeriodika
32
n3:tvurceVysledku
Svobodová, L. Gut, I. Souček, P. Anzenbacher, P. Šimek, Petr Guengerich, F. P. Václavíková, R.
n3:zamer
n14:AV0Z5007907
s:issn
0090-9556
s:numberOfPages
9