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Statements

Subject Item
n2:RIV%2F60077344%3A_____%2F13%3A00383049%21RIV14-AV0-60077344
rdf:type
n11:Vysledek skos:Concept
rdfs:seeAlso
http://www.sciencedirect.com/science/article/pii/S1095643312004904
dcterms:description
Glucagon is conventionally regarded as a hyperglycaemic hormone, which increases hepatic glucose output to the blood. Interestingly, glucagon-like peptides from the major fragment of proglucagon may also modulate response to stress in addition to their other physiological actions. These unique modes of action occur in response to stress situations and mirror the role of adipokinetic hormones (AKHs) in insects which perform a similar function. The findings on the anti-stress roles of glucagon and glucagon-like peptides in mammalian and non-mammalian vertebrates may throw light on the multiple stress responsive mechanisms which operate in a concerted manner under regulation by AKH in insects thus functioning as a stress responsive hormone. Glucagon is conventionally regarded as a hyperglycaemic hormone, which increases hepatic glucose output to the blood. Interestingly, glucagon-like peptides from the major fragment of proglucagon may also modulate response to stress in addition to their other physiological actions. These unique modes of action occur in response to stress situations and mirror the role of adipokinetic hormones (AKHs) in insects which perform a similar function. The findings on the anti-stress roles of glucagon and glucagon-like peptides in mammalian and non-mammalian vertebrates may throw light on the multiple stress responsive mechanisms which operate in a concerted manner under regulation by AKH in insects thus functioning as a stress responsive hormone.
dcterms:title
Unique roles od glucagon and glucagon-like peptides: Parallels in understanding the functions of adipokinetic hormones in stress responses in insects Unique roles od glucagon and glucagon-like peptides: Parallels in understanding the functions of adipokinetic hormones in stress responses in insects
skos:prefLabel
Unique roles od glucagon and glucagon-like peptides: Parallels in understanding the functions of adipokinetic hormones in stress responses in insects Unique roles od glucagon and glucagon-like peptides: Parallels in understanding the functions of adipokinetic hormones in stress responses in insects
skos:notation
RIV/60077344:_____/13:00383049!RIV14-AV0-60077344
n11:predkladatel
n12:ico%3A60077344
n4:aktivita
n19:I n19:P
n4:aktivity
I, P(GAP501/10/1215)
n4:cisloPeriodika
1
n4:dodaniDat
n9:2014
n4:domaciTvurceVysledku
n10:4230930 n10:9631631
n4:druhVysledku
n18:J
n4:duvernostUdaju
n6:S
n4:entitaPredkladatele
n16:predkladatel
n4:idSjednocenehoVysledku
112622
n4:idVysledku
RIV/60077344:_____/13:00383049
n4:jazykVysledku
n13:eng
n4:klicovaSlova
adipokinetic hormone; glucagon; glucagon-like peptide
n4:klicoveSlovo
n8:glucagon-like%20peptide n8:adipokinetic%20hormone n8:glucagon
n4:kodStatuVydavatele
US - Spojené státy americké
n4:kontrolniKodProRIV
[6316B24C7880]
n4:nazevZdroje
Comparative Biochemistry and Physiology A-Molecular & Integrative Physiology
n4:obor
n20:ED
n4:pocetDomacichTvurcuVysledku
2
n4:pocetTvurcuVysledku
3
n4:projekt
n7:GAP501%2F10%2F1215
n4:rokUplatneniVysledku
n9:2013
n4:svazekPeriodika
164
n4:tvurceVysledku
Krishnan, N. Bednářová, Andrea Kodrík, Dalibor
n4:wos
000312421400013
s:issn
1095-6433
s:numberOfPages
10
n14:doi
10.1016/j.cbpa.2012.10.012