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Statements

Subject Item
n2:RIV%2F60077344%3A_____%2F11%3A00369559%21RIV12-MSM-60077344
rdf:type
skos:Concept n17:Vysledek
dcterms:description
The current knowledge about Borrelia burgdorferi sl complex is summarised; morphological classification and genome organization discussed and a modern classification of Borrelia into different strains and groups is presented. The pathogenic potential of Borrelia strains not classically associated with human Lyme disease is also under discussion. The major part of the chapter is devoted to the clinical symptoms of Lyme borreliosis and to different methods of LB diagnosis with the main accent to the description of molecular approaches, PCR-based techniques in particular. It is underlined that these techniques represent rapid, reliable, simple, sensitive, cost and time-saving methods that do not require large amounts of material. In the conclusion the authors discuss the current urgent need in anti LD vaccine, the research on which is being conducted for decades already. At the moment, another generation of the vaccines – a vaccine against an arthropod vector – is under investigation. The current knowledge about Borrelia burgdorferi sl complex is summarised; morphological classification and genome organization discussed and a modern classification of Borrelia into different strains and groups is presented. The pathogenic potential of Borrelia strains not classically associated with human Lyme disease is also under discussion. The major part of the chapter is devoted to the clinical symptoms of Lyme borreliosis and to different methods of LB diagnosis with the main accent to the description of molecular approaches, PCR-based techniques in particular. It is underlined that these techniques represent rapid, reliable, simple, sensitive, cost and time-saving methods that do not require large amounts of material. In the conclusion the authors discuss the current urgent need in anti LD vaccine, the research on which is being conducted for decades already. At the moment, another generation of the vaccines – a vaccine against an arthropod vector – is under investigation.
dcterms:title
Borrelia Borrelia
skos:prefLabel
Borrelia Borrelia
skos:notation
RIV/60077344:_____/11:00369559!RIV12-MSM-60077344
n17:predkladatel
n18:ico%3A60077344
n3:aktivita
n16:P n16:Z
n3:aktivity
P(GA206/09/1782), P(LC06009), Z(AV0Z60220518)
n3:dodaniDat
n14:2012
n3:domaciTvurceVysledku
n4:9286357 n4:5005116 n4:2937204
n3:druhVysledku
n13:C
n3:duvernostUdaju
n20:S
n3:entitaPredkladatele
n6:predkladatel
n3:idSjednocenehoVysledku
188644
n3:idVysledku
RIV/60077344:_____/11:00369559
n3:jazykVysledku
n9:eng
n3:klicovaSlova
Borrelia; Ixodid ticks; Borrelia burgdorferi sensu lato coplex
n3:klicoveSlovo
n8:Ixodid%20ticks n8:Borrelia%20burgdorferi%20sensu%20lato%20coplex n8:Borrelia
n3:kontrolniKodProRIV
[264F440A1C02]
n3:mistoVydani
Boca Raton
n3:nazevZdroje
Molecular detection of human bacterial pathogens
n3:obor
n15:EE
n3:pocetDomacichTvurcuVysledku
3
n3:pocetStranKnihy
1251
n3:pocetTvurcuVysledku
4
n3:projekt
n19:LC06009 n19:GA206%2F09%2F1782
n3:rokUplatneniVysledku
n14:2011
n3:tvurceVysledku
Grubhoffer, Libor Rudenko, Natalia Golovchenko, Maryna Oliver, J. H. jr.
n3:zamer
n10:AV0Z60220518
s:numberOfPages
14
n21:hasPublisher
CRC Press, Taylor & Francis Group
n12:isbn
978-1-4398-1238-9