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Statements

Subject Item
n2:RIV%2F60077344%3A_____%2F11%3A00361426%21RIV12-MSM-60077344
rdf:type
n18:Vysledek skos:Concept
dcterms:description
Tick-borne encephalitis virus (TBEV) causes one of the most important flavivirus infections of the central nervous system, affecting humans in Europe and Asia. To test the suitability of rodents as a surrogate marker for virus spread, laboratory-bred Microtus arvalis voles were experimentally infected with TBEV and analyzed over a period of 100 days by real-time (RT)-quantitative PCR. Further, the prevalence of TBEV in rodents trapped in Brandenburg (Germany) was determined. In experimentally infected M. arvalis voles, TBEV was detectable in different organs for at least 3 months and in blood for 1 month. 10% of all rodents investigated were positive for TBEV. TBEV was detected in 6 rodent species: Apodemus agrarius, Apodemus flavicollis, Apodemus sylvaticus, Microtus agrestis, Microtus arvalis, and Myodes glareolus. M. glareolus showed a high infection rate in all areas investigated. These voles developed a persistent TBE infection without clinical symptoms. Tick-borne encephalitis virus (TBEV) causes one of the most important flavivirus infections of the central nervous system, affecting humans in Europe and Asia. To test the suitability of rodents as a surrogate marker for virus spread, laboratory-bred Microtus arvalis voles were experimentally infected with TBEV and analyzed over a period of 100 days by real-time (RT)-quantitative PCR. Further, the prevalence of TBEV in rodents trapped in Brandenburg (Germany) was determined. In experimentally infected M. arvalis voles, TBEV was detectable in different organs for at least 3 months and in blood for 1 month. 10% of all rodents investigated were positive for TBEV. TBEV was detected in 6 rodent species: Apodemus agrarius, Apodemus flavicollis, Apodemus sylvaticus, Microtus agrestis, Microtus arvalis, and Myodes glareolus. M. glareolus showed a high infection rate in all areas investigated. These voles developed a persistent TBE infection without clinical symptoms.
dcterms:title
Rodents as Sentinels for the Prevalence of Tick-Borne Encephalitis Virus Rodents as Sentinels for the Prevalence of Tick-Borne Encephalitis Virus
skos:prefLabel
Rodents as Sentinels for the Prevalence of Tick-Borne Encephalitis Virus Rodents as Sentinels for the Prevalence of Tick-Borne Encephalitis Virus
skos:notation
RIV/60077344:_____/11:00361426!RIV12-MSM-60077344
n18:predkladatel
n19:ico%3A60077344
n5:aktivita
n13:Z n13:P
n5:aktivity
P(GPP302/10/P438), P(LC06009), Z(AV0Z60220518)
n5:cisloPeriodika
6
n5:dodaniDat
n12:2012
n5:domaciTvurceVysledku
n20:8473900
n5:druhVysledku
n7:J
n5:duvernostUdaju
n9:S
n5:entitaPredkladatele
n15:predkladatel
n5:idSjednocenehoVysledku
227334
n5:idVysledku
RIV/60077344:_____/11:00361426
n5:jazykVysledku
n14:eng
n5:klicovaSlova
Distribution; Monitoring; Rodents; Tick-borne encephalitis; Zoonosis
n5:klicoveSlovo
n8:Monitoring n8:Tick-borne%20encephalitis n8:Rodents n8:Distribution n8:Zoonosis
n5:kodStatuVydavatele
US - Spojené státy americké
n5:kontrolniKodProRIV
[D20C86A7BB5D]
n5:nazevZdroje
Vector-Borne and Zoonotic Diseases
n5:obor
n6:EE
n5:pocetDomacichTvurcuVysledku
1
n5:pocetTvurcuVysledku
14
n5:projekt
n11:GPP302%2F10%2FP438 n11:LC06009
n5:rokUplatneniVysledku
n12:2011
n5:svazekPeriodika
11
n5:tvurceVysledku
Donoso-Mantke, O. Vor, T. Ali, H. S. Achazi, K. Schmidt-Chanasit, J. Kallies, R. Schlegel, M. Ohlmeyer, L. Ruhe, F. Niedrig, M. Růžek, Daniel Wenk, M. Kiffner, Ch. Ulrich, R. G.
n5:wos
000291717500009
n5:zamer
n10:AV0Z60220518
s:issn
1530-3667
s:numberOfPages
7
n17:doi
10.1089/vbz.2010.0236